Effect of vitamin-mineral complexes on quality of life of patients with arterial hypertension

Objective: A considerable proportion of the population due to both economic reasons and traditions appear to be experiencing chronic deficit in micronutrients, which may be deteriorated on the background of drug therapy being performed. The purpose of our study was to optimize pharmacotherapy of pat...

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Bibliographic Details
Published in:Electronic journal of general medicine 2018-01, Vol.15 (4), p.em41
Main Authors: Shikh, Evgeniya V., Lapidus, Natalya I., Tyazhelnikov, Andrey A., Karaulov, Alexander V., Drozdov, Vladimir N., Trukhin, Ivan V.
Format: Article
Language:English
Subjects:
Antihypertensives
Drug therapy
Hypertension
Neuropsychology
Quality of life
Questionnaires
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Summary:Objective: A considerable proportion of the population due to both economic reasons and traditions appear to be experiencing chronic deficit in micronutrients, which may be deteriorated on the background of drug therapy being performed. The purpose of our study was to optimize pharmacotherapy of patients with first-ever prescribed diuretic-containing combined therapy for arterial hypertension (AH) by means of adding a vitamin-mineral complex. Method: To determine B-group vitamins (thiamine, riboflavin, pyridoxine) in blood plasma by means of high-performance liquid chromatography (HPLC) and, on achieving the target values of arterial pressure (AP), to analyse the patients’ quality of life by means of such neuropsychological tests as the General Health Questionnaire – 36 (GHQ-36) and WAM (wellbeing, activity, mood) questionnaire. Results: The group of patients receiving antihypertensive therapy alone demonstrated a decrease in blood plasma thiamine, riboflavin and pyridoxine from 34.5±4.2 to 25.4±3.2 ng/ml (p
ISSN:2516-3507
2516-3507
DOI:10.29333/ejgm/85025