Preoperative Serum IL-6 Levels: Clinical Importance in Gastric Carcinoma with Lymph Node Metastasis

Aim: The interleukin-6 (IL-6) pathway is one of the mechanisms that link inflammation and angiogenesis. The purpose of this study was to investigate the preoperative serum levels of IL-6 in gastric carcinoma with lymph node metastasis, and to correlate them with disease status. Method: A total of 10...

Full description

Saved in:
Bibliographic Details
Published in:Electronic journal of general medicine 2010-10, Vol.7 (4), p.410-413
Main Authors: Kemik, Özgür, Sümer, Aziz, Kemik, Ahu Sarbay, Dülger, A Cumhur, Hasırcı, İsmail, Adaş, Mine, Purisa, Sevim, Tüzün, Sefa
Format: Article
Language:English
Subjects:
Cancer
Lymphatic system
Metastasis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aim: The interleukin-6 (IL-6) pathway is one of the mechanisms that link inflammation and angiogenesis. The purpose of this study was to investigate the preoperative serum levels of IL-6 in gastric carcinoma with lymph node metastasis, and to correlate them with disease status. Method: A total of 100 patients who underwent gastrectomy were enrolled in this study. Serum levels of IL-6 were assessed enzyme linked immunosorbent assay (ELISA). Histological findings included tumor size, depth of tumor invasion, lymph node (LN) metastasis, and TNM stage.Result:Increases in cancer invasion and staging are generally associated with increases in preoperative serum IL-6 levels. IL-6 levels were correlated with invasion depth (p
ISSN:2516-3507
2516-3507
DOI:10.29333/ejgm/82894