Antagonistic effect of 6-hydroxydopamine (6-OHDA) on generation of immunosuppressive protein of stress in the rat

Neonatal rats were injected with 6-hydroxydopamine (6-OHDA) for chemical sympathectomy. The rats were treated with restraint stress when they grew up to 56 d. It has-been found that the generation of immunosuppressive protein of stress (ISPS) is significantly reduced, suggesting that peripheral symp...

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Bibliographic Details
Published in:Chinese science bulletin 1999-11, Vol.44 (21), p.1974-1978
Main Authors: Li, Juxiang, Shao, Li, Li, Yifan, Mei, Lin, Fan, Shaoguang
Format: Article
Language:English
Subjects:
6-Hydroxydopamine
Neonates
Proteins
Sympathetic nerves
Sympathetic nervous system
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Summary:Neonatal rats were injected with 6-hydroxydopamine (6-OHDA) for chemical sympathectomy. The rats were treated with restraint stress when they grew up to 56 d. It has-been found that the generation of immunosuppressive protein of stress (ISPS) is significantly reduced, suggesting that peripheral sympathetic nerve plays an important role in mediating the generation of ISPS.
ISSN:1001-6538
2095-9273
1861-9541
2095-9281
DOI:10.1007/BF02887122