1 Year) Cardiac Outcomes of Peripartum Cardiomyopathy

Peripartum cardiomyopathy is the development of heart failure toward the end of pregnancy or in the months after delivery in the absence of other attributable causes, with left ventricular systolic dysfunction and a left ventricular ejection fraction (LVEF) generally 1 year) patient outcomes. Of the...

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Bibliographic Details
Published in:The American journal of cardiology 2023-05, Vol.194, p.71
Main Authors: Koerber, Daniel, Khan, Shawn, Kirubarajan, Abirami, Spivak, Alexandra, Wine, Rachel, Matelski, John, Sobel, Mara, Harris, Kristin
Format: Article
Language:English
Subjects:
Bias
Body mass index
Cardiomyopathy
Cardiovascular diseases
Cohort analysis
Congestive heart failure
Defibrillators
Diabetes
Diagnosis
Dyspnea
Health risks
Heart failure
Heart transplantation
High income
Hypertension
Implantation
Industrialized nations
Medical prognosis
Meta-analysis
Mortality
Patients
Risk factors
Systematic review
Transplantation
Ventricle
Ventricular assist devices
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Summary:Peripartum cardiomyopathy is the development of heart failure toward the end of pregnancy or in the months after delivery in the absence of other attributable causes, with left ventricular systolic dysfunction and a left ventricular ejection fraction (LVEF) generally 1 year) patient outcomes. Of the 3,144 total records identified, 62 studies involving 4,282 patients met the selection criteria. The mean LVEF was 28% at diagnosis and 47% at the time of the last follow-up. Approximately half of the patients achieved myocardial recovery (47%), most commonly defined as an LVEF >50% (n = 21). The prevalence of implantable cardioverter-defibrillator use, left ventricular assist device implantation, and heart transplantation was 12%, 7%, and 11%, respectively. The overall all-cause mortality was 9%, and despite having more cardiovascular risk factors, patients residing in high-income countries had superior outcomes, including reduced rates of mortality.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2023.01.043