Borderline Personality Disorder: Refinements in Phenotypic and Cognitive Profiling

Purpose of Review Advancements in taxometric and dimensional approaches to personality psychopathology have pushed for refinements to the borderline personality disorder (BPD) phenotype, but proposed revisions to the diagnosis in major nosological systems hinge in part on evidence to support their v...

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Bibliographic Details
Published in:Current behavioral neuroscience reports 2018-03, Vol.5 (1), p.102-112
Main Authors: Koudys, Jacob W., Gulamani, Tahira, Ruocco, Anthony C.
Format: Article
Language:English
Subjects:
Behavioral Therapy
Biomarkers
Borderline personality disorder
Endorsements
Genotype & phenotype
Latent class analysis
Medicine
Medicine & Public Health
Mental disorders
Neurology
Pediatrics
Personality and Impulse Control Disorders (R Lee
Personality disorders
Psychiatry
Revisions
Section Editor
Topical Collection on Personality and Impulse Control Disorders
Validity
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Summary:Purpose of Review Advancements in taxometric and dimensional approaches to personality psychopathology have pushed for refinements to the borderline personality disorder (BPD) phenotype, but proposed revisions to the diagnosis in major nosological systems hinge in part on evidence to support their validity. We review recent phenotypic and cognitive research on BPD and consider ways that changes to the phenotype may be validated using cognitive measures. Recent Findings Phenotypic research on BPD has identified core symptom dimensions underlying the DSM diagnosis, which also aggregate in families. While a unidimensional model of the disorder has been found in some studies, latent subgroups within the diagnosis have also been uncovered. Cognitive findings reveal deficits primarily in executive functions relevant to self-regulation but also in episodic memory and attentional abilities. Summary Cognitive functioning should be considered as a potential validator of proposed changes or refinements to the BPD phenotype, including categorical and dimensional conceptualizations.
ISSN:2196-2979
2196-2979
DOI:10.1007/s40473-018-0145-x