Bacteremia as a risk factor for variceal upper gastrointestinal tract bleeding in cirrhotic patients: a hospital-based study

Background The presence of bacteremia as a complication of variceal bleeding in patients with liver cirrhosis had been investigated by many studies. The aim of this study was to assess the bacteremia as a risk factor for variceal upper gastrointestinal tract bleeding in cirrhotic patients. A cross-s...

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Bibliographic Details
Published in:Egyptian Liver Journal 2021-01, Vol.11 (1), p.8-7
Main Authors: Zidan, Mohamad Husseini Saeid, Zaghloul, Sahar Gouda, Seleem, Waseem Mohamed, Ahmed, Hanan Samir, Gad, Ahmed Ibrahim
Format: Article
Language:English
Subjects:
Ascites
Bacteremia
Bacterial infections
Blood
Chronic illnesses
Cirrhosis
Creatinine
Gastrointestinal system
Hemoglobin
Hospitals
Hypertension
Infections
Laboratories
Liver
Liver cirrhosis
Liver diseases
Medical examination
Medical research
Medicine, Experimental
Patients
PCT
Risk factors
Sepsis
Statistical analysis
Variceal bleeding
Viral infections
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Summary:Background The presence of bacteremia as a complication of variceal bleeding in patients with liver cirrhosis had been investigated by many studies. The aim of this study was to assess the bacteremia as a risk factor for variceal upper gastrointestinal tract bleeding in cirrhotic patients. A cross-sectional study was conducted on 99 patients with chronic liver disease divided into three groups: group I included 35 patients presented with first attack of variceal bleeding, group II included 35 patients presented with recurrent attacks of variceal bleeding, and group III included 29 patients with no history of previous variceal bleeding as a control group. Routine laboratory tests were done, upper GI endoscopy, blood culture, and measurement of procalcitonin level in blood. Results Patients with recurrent variceal bleeding had statistically (p 1.76 is the most specific in predicting bleeding 86.21%, 86.21% (CI 95%) respectively. Conclusion Bacteremia and procalcitonin are risk factor for variceal bleeding in cirrhotic patients. Procalcitonin can be used as easily measurable and surrogate biomarker for bacteremia and variceal bleeding.
ISSN:2090-6218
2090-6226
DOI:10.1186/s43066-021-00078-8