K2S2O8‐induced Dearomative Spirocyclization of Biaryl Ynones with Diselenides toward Selenated Spirotrienones

A metal‐free radical spirocyclization of biaryl ynones with diselenides is developed, providing selenated spiro[5.5]trienones in moderate to good yields. This protocol features broad substrate scope, good functional group tolerance and free of an inert atmosphere. Furthermore, the replacement of dis...

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Bibliographic Details
Published in:Asian journal of organic chemistry 2023-05, Vol.12 (5)
Main Authors: Yu, Lanbin, Peng, Yingzhi
Format: Article
Language:English
Subjects:
Free radicals
Functional groups
Inert atmospheres
Organic chemistry
Potassium persulfate
Selenides
Substrates
Tellurium
Online Access:Get full text
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Summary:A metal‐free radical spirocyclization of biaryl ynones with diselenides is developed, providing selenated spiro[5.5]trienones in moderate to good yields. This protocol features broad substrate scope, good functional group tolerance and free of an inert atmosphere. Furthermore, the replacement of diselenides with ditellurides is also applicable for this reaction to construct the corresponding tellurium‐substituted spiro[5.5]trienones.
ISSN:2193-5807
2193-5815
DOI:10.1002/ajoc.202300086