Gold nanoparticle-decorated MoSe2 nanosheets as highly effective peroxidase-like nanozymes for total antioxidant capacity assay

A visual colorimetric detection strategy is reported for total antioxidant capacity (TAC) assay by using 3,3′,5,5′-tetramethylbenzidine (TMB) oxidation as chromogenic substrate based on gold nanoparticle-decorated MoSe 2 nanosheets (Au@MoSe 2 ). Au@MoSe 2 nanostructures exhibit high peroxidase-like...

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Bibliographic Details
Published in:Nano research 2023-05, Vol.16 (5), p.7180-7186
Main Authors: Hong, Chengyi, Chen, Lingling, Huang, Jiayi, Shen, Yunling, Yang, Hongfen, Huang, Zhiyong, Cai, Ren, Tan, Weihong
Format: Article
Language:English
Subjects:
Antigens
Antioxidants
Ascorbic acid
Assaying
Atomic/Molecular Structure and Spectra
Beverages
Biomedicine
Biotechnology
Carbon
Chemistry and Materials Science
Colorimetry
Condensed Matter Physics
Enzymes
Food
Food quality
Glucose
Gold
Graphene
Hydrogen peroxide
Materials Science
Molybdenum compounds
Nanomaterials
Nanoparticles
Nanosheets
Nanostructure
Nanotechnology
Oxidation
Peroxidase
Photocatalysis
Research Article
Substrates
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Summary:A visual colorimetric detection strategy is reported for total antioxidant capacity (TAC) assay by using 3,3′,5,5′-tetramethylbenzidine (TMB) oxidation as chromogenic substrate based on gold nanoparticle-decorated MoSe 2 nanosheets (Au@MoSe 2 ). Au@MoSe 2 nanostructures exhibit high peroxidase-like activity and can catalyze H 2 O 2 to oxidize TMB. Based on inhibition effect of ascorbic acid (AA) on TMB oxidation, a facile and sensitive colorimetric method was developed for AA detection. Under optimal conditions, the proposed method showed a sensitivity for AA in a concentration range from 2 to 120 µM and limit of detection was 0.41 µM. Furthermore, the method was employed for TAC assay in actual samples, including commercial beverages and vitamin C tablets. This work represents a model in nanostructure design and will lead to further development of TAC assay in evaluation of antioxidant food quality.
ISSN:1998-0124
1998-0000
DOI:10.1007/s12274-022-5328-9