Determination of Antioxidant Properties and Antimicrobial Activity of Vinyl Phenolic Compounds Extracted from Saccharomyces Cerevisiae Against Uropathogenic Bacteria

This research study aimed at determining the vinyl phenolic compounds with antioxidant properties and antimicrobial activity using acetone and methanol extracts of Saccharomyces cerevisiae (S. cerevisiae) The HPLC-UV technique was employed for the identification of the vinyl phenolic compounds and F...

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Bibliographic Details
Published in:Oriental journal of chemistry 2020-01, Vol.36 (1), p.26-32
Main Authors: Sheriff Maqbul, Muazzam, Khan, Aejaz A., Mohammed, Tasneem, Shakeel Iquba, S. M., Ahmed Shaikh, Ibrahim, Muddapur, Uday M., Basha Sheik, Gouse, Singh, S. K., Shahid Hussain, Mohammed, Gamal, Mohammed
Format: Article
Language:English
Subjects:
Acids
Antibiotics
Antiinfectives and antibacterials
Antimicrobial agents
Antioxidants
Chemicals
E coli
Glycosides
Identification
Metabolites
Oxidative stress
Oxidizing agents
Phenols
Physiology
Reagents
Scavenging
Signal transduction
Urogenital system
Yeast
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Summary:This research study aimed at determining the vinyl phenolic compounds with antioxidant properties and antimicrobial activity using acetone and methanol extracts of Saccharomyces cerevisiae (S. cerevisiae) The HPLC-UV technique was employed for the identification of the vinyl phenolic compounds and Ferric and Ferrous reducing anti-oxidant power assay along with radical scavenging methods were applied to determine the anti-oxidant properties of the yeast extract. The biochemical tests showed the presence of alkaloids, reducing sugars, steroid, proteins, phenol, cardiac glycosides and glycosides. Further antimicrobial properties of the yeast extract using Kirby-Bauer disc diffusion method indicates, E.coli exhibits the best susceptibility towards the yeast extract. The antimicrobial susceptibility was excellent for all the isolated uropathogens when compared with the standard antibiotics. The metabolites produced by the yeast exhibits vital pharmaceutical important substances such as analgesic, antipyretic, anti-proliferative and antimicrobial properties. This study is a small attempt towards a larger future to serve the mankind with natural remedies.
ISSN:0970-020X
2231-5039
DOI:10.13005/ojc/360104