The effect of ethanol percentage as solvent towards antioxidant activity of Picria fel-terrae Lour. herbs

Antioxidants are compounds that can counteract or mitigate the negative effects of oxidants in the body, works by donating an electron to compounds that are oxidant so that the oxidant compound activity can be inhibited. Poguntano (Picria fel-terrae Lour.) is a plant which is known antioxidant effec...

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Bibliographic Details
Main Authors: Dalimunthe, Aminah, Pertiwi, Dewi, Muhammad, Mahatir, Asfianti, Vivi, Satria, Denny
Format: Conference Proceeding
Language:English
Subjects:
Aluminum chloride
Antioxidants
Ethanol
Flavonoids
Functional foods & nutraceuticals
Herbs
Oxidation
Oxidizing agents
Solvents
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Summary:Antioxidants are compounds that can counteract or mitigate the negative effects of oxidants in the body, works by donating an electron to compounds that are oxidant so that the oxidant compound activity can be inhibited. Poguntano (Picria fel-terrae Lour.) is a plant which is known antioxidant effect. This study was aimed to analyze antioxidant activity, total phenolic content and total flavonoid content in ethanol extract (EE). The powder was extracted by maceration method with ethanol 100%, 90%, 80%, 70%, 60% and 50%. Antioxidant activity was analysed with 1,1-diphenyl-2-picrylhydrazyl (DPPH), and Ferric Reducing Antioxidant Power (FRAP). Total phenolic content was measured using the Folin-Ciocalteau method and total flavonoid content was measured using AlCl3 colorimetric method. The best antioxidant activity was showed by ethanol extract with solvent ethanol (EEP) 100% with IC50 10.68 ± 0.17µg/mL (DPPH method), 18.15 ± 0.24 µg/mL (FRAP method), and high level of total phenolic content (279.11 ± 0.51mg GAE/g), high level of total flavonoid content (31.90 ± 0.46 mg QE/g). In conclusion, the ethanol extract of Picria fel-terrae Lour herbs can be further developed as an antioxidant and functional food.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0136102