Biodetoxification of Aflatoxin B1 by Arthrospira platensis in Broilers

• Published in: Journal of applied phycology 2023-06, Vol.35 (3), p.1193-1201
• Main Authors: Kasmani, Farzad Bagherzadeh, Javaremi, Ardeshir Nejati, Ghazaghi, Mahmoud
• Format: Article
• Language: English
• Subjects: Aflatoxin B1; Aflatoxins; Antioxidants; Arthrospira platensis; Bacteria; Biomedical and Life Sciences; Body weight; Body weight gain; Chicks; Coliforms; Contamination; Conversion ratio; Defence mechanisms; Diet; Dietary supplements; Ecology; Enzymatic activity; Enzyme activity; Enzymes; Feed conversion; Feeds; Food conversion; Freshwater & Marine Ecology; Green products; Immune response; Immune response (humoral); Immune system; Immunity; Intestinal microflora; Intestine; Intestines; Juveniles; Lactic acid; Lactic acid bacteria; Life Sciences; Liver; Microbiota; Microorganisms; Oxidative stress; Parameters; Plant Physiology; Plant Sciences; Poultry; Serum
• ISSN: 0921-8971; 1573-5176
• DOI: 10.1007/s10811-023-02962-9

An experiment was conducted to determine the effects of Arthrospira platensis (AP) on the growth performance, serum enzyme activity, liver oxidative stress markers as well as antioxidant parameters, intestinal microbiota, and humoral immune response of broilers fed aflatoxin B 1 (AFB 1 ) contaminated diet. A total of 200 one-day-old Ross 308 broiler chicks were assigned to four treatments, control (basal diet), aflatoxin (AF) contaminated diet (basal diet + 2.5 mg AFB 1 kg −1 ), AP diet (basal diet + 1000 mg AP kg −1 ), and AFAP diet (basal diet + 2.5 mg AFB 1 and 1000 mg AP kg −1 ) with five replicate pens and 10 broiler chicks per pen. Arthrospira platensis was able to neutralize the effect of AFB 1 , increase the body weight gain and feed intake, while reducing the feed conversion ratio. Liver damage marker enzymes in the serum sharply increased by AFB 1 in feed (AF group), while supplementation of aflatoxin-contaminated diet with AP reduced the level of these enzymes ( p