Dansyl-triazole-based fluorescent macrocycle for selective detection of nitro-antibiotic drugs and protein interaction

A novel dansyl-triazole-based fluorescent macrocycle with high Stokes shift and positive solvatochromism was developed. This is an excellent fluorescence sensor for selective detection of nitro-containing antibiotics and other nitro-heteroaromatics. Detection was possible in real samples/paper strip...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2023-06, Vol.59 (48), p.7399-742
Main Authors: Thurakkal, Liya, Mol, Rakhi, Porel, Mintu
Format: Article
Language:English
Subjects:
Antibiotics
Fluorescence
Fluorescent Dyes
Limit of Detection
Proteins
Spectrometry, Fluorescence
Triazoles
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Summary:A novel dansyl-triazole-based fluorescent macrocycle with high Stokes shift and positive solvatochromism was developed. This is an excellent fluorescence sensor for selective detection of nitro-containing antibiotics and other nitro-heteroaromatics. Detection was possible in real samples/paper strips in submicromolar concentration. The interaction of the macrocycle with multiple proteins exhibited its bioactivity. A novel dansyl-triazole-based fluorescent macrocycle with high Stokes shift and positive solvatochromism has been developed for sensing nitro-containing antibiotics from real water and in paper strips.
ISSN:1359-7345
1364-548X
DOI:10.1039/d3cc01769a