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Synthesis of 2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetamides

Ethyl 2-[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetate reacted with aliphatic amines to give the corresponding acetamides, whereas its reactions with hydrazine hydrate and aniline afforded 2-hydrazinyl- and 2-anilino-6-methylpyrimidin-4(3 H )-ones, respectively.

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Bibliographic Details
Published in:Russian journal of organic chemistry 2023-04, Vol.59 (4), p.738-742
Main Authors: Shiryaev, A. K., Gulyaeva, A. M., Shiryaev, V. A., Aristova, U. M.
Format: Article
Language:English
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Summary:Ethyl 2-[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetate reacted with aliphatic amines to give the corresponding acetamides, whereas its reactions with hydrazine hydrate and aniline afforded 2-hydrazinyl- and 2-anilino-6-methylpyrimidin-4(3 H )-ones, respectively.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428023040255