Synthesis of 2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetamides

Ethyl 2-[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetate reacted with aliphatic amines to give the corresponding acetamides, whereas its reactions with hydrazine hydrate and aniline afforded 2-hydrazinyl- and 2-anilino-6-methylpyrimidin-4(3 H )-ones, respectively.

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Published in:Russian journal of organic chemistry 2023-04, Vol.59 (4), p.738-742
Main Authors: Shiryaev, A. K., Gulyaeva, A. M., Shiryaev, V. A., Aristova, U. M.
Format: Article
Language:English
Subjects:
Aliphatic amines
Aniline
Chemistry
Chemistry and Materials Science
Hydrazines
Organic Chemistry
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Aristova, U. M.
description Ethyl 2-[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetate reacted with aliphatic amines to give the corresponding acetamides, whereas its reactions with hydrazine hydrate and aniline afforded 2-hydrazinyl- and 2-anilino-6-methylpyrimidin-4(3 H )-ones, respectively.
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source Springer Nature
subjects Aliphatic amines
Aniline
Chemistry
Chemistry and Materials Science
Hydrazines
Organic Chemistry
title Synthesis of 2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetamides
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