Obstructive Uropathy in Advanced Prostate Cancer

Objective: The incidence of advanced prostate cancer increases in proportion to new treatment options and prolonged life expectancy. Especially in advanced disease, prostate cancer is a progressive disease that can cause obstructive uropathy. This study investigated the relationship between the char...

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Bibliographic Details
Published in:Üroonkoloji bülteni 2023-06, Vol.22 (2), p.57-61
Main Authors: Erbatu, Oğuzcan, Müezzinoğlu, Talha
Format: Article
Language:English
Subjects:
Biopsy
Cancer therapies
Chemotherapy
Creatinine
Hydronephrosis
Life expectancy
Metastasis
Monte Carlo simulation
Patients
Prostate cancer
Urinary tract infections
Urine
Urogenital system
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Summary:Objective: The incidence of advanced prostate cancer increases in proportion to new treatment options and prolonged life expectancy. Especially in advanced disease, prostate cancer is a progressive disease that can cause obstructive uropathy. This study investigated the relationship between the characteristics of advanced prostate cancer and obstructive uropathy. Materials and Methods: This study retrospectively evaluated the data of prostate adenocarcinoma patients admitted to the Urology Clinic of Manisa Celal Bayar University Hospital between 2017 and 2021. Of them, 48 were advanced prostate cancer patients, and they were all included. All patients in the study received hormonal therapy along with chemotherapy for prostate cancer treatment. The relationship between hydronephrosis and patient age, creatinine and prostate-specific antigen (PSA) values, urinary tract infections, prostate volume, pathological features of cancer, and castration resistance was evaluated. Results: Parameters that we found to be associated with obstructive uropathy (OU) are as follows: high creatinine level at the time of diagnosis of cancer (p
ISSN:2147-2122
2147-2270
DOI:10.4274/uob.galenos.2022.2022.10.6