Why to Study Peptides from Venomous and Poisonous Animals?

Venom and poison peptides are powerful biological weapons and have proven immense pharmacological potential because of their high binding affinity to a wide range of molecular targets. Nonetheless, many of these peptides cannot directly be used as medicines due to their toxicity but their derivative...

Full description

Saved in:
Bibliographic Details
Published in:International journal of peptide research and therapeutics 2023-07, Vol.29 (5), p.76, Article 76
Main Authors: de Oliveira, Ana Novo, Soares, Andreimar Martins, Da Silva, Saulo Luís
Format: Article
Language:English
Subjects:
Animal Anatomy
Animals
Biochemistry
Biological & chemical weapons
Biomedical and Life Sciences
Drug development
Drugs
Enzymes
FDA approval
Histology
Inflammatory diseases
Life Sciences
Molecular Medicine
Morphology
Organisms
Peptides
Pharmaceutical Sciences/Technology
Pharmacology/Toxicology
Physiology
Poisons
Polymer Sciences
Reptiles & amphibians
Snake bites
Toxicity
Toxins
Venom
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Venom and poison peptides are powerful biological weapons and have proven immense pharmacological potential because of their high binding affinity to a wide range of molecular targets. Nonetheless, many of these peptides cannot directly be used as medicines due to their toxicity but their derivatives are very valuable to explore and can be a great treasure trove for the development of novel drugs. This review presents a detailed overview of venom peptides present in reptiles, amphibians, arachnids, gastropods, clitellatas, fish, insects, and mammals. We address the most recent findings that underline their therapeutic potential against a wide variety of diseases from cancer to vascular, autoimmune, and inflammatory diseases. Graphical Abstract
ISSN:1573-3904
1573-3149
1573-3904
DOI:10.1007/s10989-023-10543-0