Review on modelling approaches of thermoregulation mechanisms

Diverse physiological processes have evolved for humans to maintain a core body temperature of around 37 °C in response to various diseases and environmental conditions. Using a computational model to predict temperature responses has provided new insights for diagnosing clinical conditions, designi...

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Bibliographic Details
Published in:Journal of thermal analysis and calorimetry 2023-09, Vol.148 (17), p.9343-9360
Main Authors: Chithramol, M. K., Shine, S. R.
Format: Article
Language:English
Subjects:
Analytical Chemistry
Body temperature
Chemistry
Chemistry and Materials Science
Heat exchange
Inorganic Chemistry
Mathematical models
Measurement Science and Instrumentation
Modelling
Physical Chemistry
Polymer Sciences
Protective clothing
Shivering
Thermoregulation
Vasoconstriction
Vasodilation
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Summary:Diverse physiological processes have evolved for humans to maintain a core body temperature of around 37 °C in response to various diseases and environmental conditions. Using a computational model to predict temperature responses has provided new insights for diagnosing clinical conditions, designing protective clothing, conducting climate research, etc. This article summarizes the modelling methodologies used for active thermoregulation mechanisms such as vasoconstriction, shivering, vasodilation, and sweating. The review examines briefly the fundamental principles of human thermoregulation, the main milestones in the development of mathematical models, and the empirical formulas found in the scientific literature for modelling the body’s responses to heat/cold stress. Summary of the modelling of the response mechanism and the associated changes in the heat exchange between the human body and the environment are also provided.
ISSN:1388-6150
1588-2926
DOI:10.1007/s10973-023-12132-1