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Bioorthogonally Assisted Phototherapy: Recent Advances and Prospects

Photoresponsive materials offer excellent spatiotemporal control over biological processes and the emerging phototherapeutic methods are expected to have significant effects on targeted cancer therapies. Recent examples show that combination of photoactivatable approaches with bioorthogonal chemistr...

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Bibliographic Details
Published in:Angewandte Chemie 2023-08, Vol.135 (33), p.n/a
Main Authors: Kozma, Eszter, Bojtár, Márton, Kele, Péter
Format: Article
Language:English
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Summary:Photoresponsive materials offer excellent spatiotemporal control over biological processes and the emerging phototherapeutic methods are expected to have significant effects on targeted cancer therapies. Recent examples show that combination of photoactivatable approaches with bioorthogonal chemistry enhances the precision of targeted phototherapies and profound implications are foreseen particularly in the treatment of disperse/diffuse tumors. The extra level of on‐target selectivity and improved spatial/temporal control considerably intensified related bioorthogonally assisted phototherapy research. The anticipated growth of further developments in the field justifies the timeliness of a brief summary of the state of the art. Phototherapeutic approaches combined with bioorthogonal chemistry are expected to significantly improve the spatiotemporal precision of targeted therapies. As a result, related bioorthogonally assisted phototherapy research has recently intensified. This minireview briefly discusses the latest developments in the state of the art.
ISSN:0044-8249
1521-3757
DOI:10.1002/ange.202303198