Platelet-Rich Stroma (PRS) Injection Provides Great Improvement in Depressed Scars

  Patients who have depressed scars experience both psychological and esthetic problems. However, multi-modality treatment was preferred because no single treatment is sufficient on its own. The authors hypothesize that injections of stromal vascular fraction (SVF) combined with platelet-rich plasma...

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Published in:Indian journal of surgery 2023-08, Vol.85 (4), p.905-911
Main Authors: Liu, Xiaojie, Wang, Zihan, Zhang, Wenan, Shi, Ting, Wang, Yun, Liu, Guanying
Format: Article
Language:English
Subjects:
Blood platelets
Cardiac Surgery
Medicine
Medicine & Public Health
Neurosurgery
Original Article
Pediatric Surgery
Plasma
Plastic Surgery
Regenerative medicine
Scars
Surgery
Thoracic Surgery
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container_end_page 911
container_issue 4
container_start_page 905
container_title Indian journal of surgery
container_volume 85
creator Liu, Xiaojie
Wang, Zihan
Zhang, Wenan
Shi, Ting
Wang, Yun
Liu, Guanying
description   Patients who have depressed scars experience both psychological and esthetic problems. However, multi-modality treatment was preferred because no single treatment is sufficient on its own. The authors hypothesize that injections of stromal vascular fraction (SVF) combined with platelet-rich plasma (PRP) as a new autologous treatment can improve depressed scars effectively. According to the inclusion criteria, 20 patients with depressed scars resulting from various causes were observed in the research. A single injection of harvestable PRS (combination of PRP and SVF) was administered to all patients as part of the treatment. The POSAS scale was used to evaluate scars both pre- and postoperatively at 6 months. A paired t -test was used to determine whether the scar features and symptoms had improved. Photographic comparisons were taken before and after the surgery. The degree of improvement of the depressed scar was graded, and the efficacy was evaluated using the POSAS total score. Before and 6 months after therapy, there were statistically significant variations in the scar index values ( P  
doi_str_mv 10.1007/s12262-022-03588-w
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Before and 6 months after therapy, there were statistically significant variations in the scar index values ( P  &lt; 0.05). The overall efficacy rate (17/20) was 85% among all patients, with 12 cases of tertiary improvement and 5 cases of improvement in grade 4. There were no lumps or cord-like indurations in the filling sites of the 20 patients. 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subjects Blood platelets
Cardiac Surgery
Medicine
Medicine & Public Health
Neurosurgery
Original Article
Pediatric Surgery
Plasma
Plastic Surgery
Regenerative medicine
Scars
Surgery
Thoracic Surgery
title Platelet-Rich Stroma (PRS) Injection Provides Great Improvement in Depressed Scars
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