Visible‐Light‐Driven Sulfonamidation of Arylazo Sulfonesthrough One‐Pot Multicomponent Reaction

Sulfonamide is one of the most important structures in organic chemistry due to its frequent appearance in natural products as well as pharmaceuticals. This study reports a visible‐light‐promoted strategy for synthesis of sulfonamides from arylazo sulfones. One‐pot tri‐component reactions were condu...

Full description

Saved in:
Bibliographic Details
Published in:Asian journal of organic chemistry 2023-08, Vol.12 (8), p.n/a
Main Authors: Luu, Truong Giang, Kim, Hee‐Kwon
Format: Article
Language:English
Subjects:
Amines
arylazo sulfones
Copper bromide
DABSO
multicomponent reaction
Natural products
Organic chemistry
Sulfonamide
Sulfonamides
Sulfones
visible-light-induced-reaction
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sulfonamide is one of the most important structures in organic chemistry due to its frequent appearance in natural products as well as pharmaceuticals. This study reports a visible‐light‐promoted strategy for synthesis of sulfonamides from arylazo sulfones. One‐pot tri‐component reactions were conducted using arylazo sulfones, DABSO, and amines in the presence of CuBr2 as a coupling catalyst under irradiation with blue LEDs to prepare various sulfonamides in good yields under mild conditions. This method could be used effectively to produce a variety of useful sulfonamides. Visible‐light‐mediated synthesis of sulfonamides via one‐pot reaction is developed. One‐pot reactions were successfully carried out using arylazo sulfones, DABSO, and amines in the presence of CuBr2 under blue LEDs light to generate various sulfonamides in good yields under mild conditions.
ISSN:2193-5807
2193-5815
DOI:10.1002/ajoc.202300301