Microemulsions in Systems with Lecithin and Oleic Acid for Medical Use

Reverse microemulsions for use in medicine and cosmetics in systems containing lecithin (a mixture of phospholipids with a lecithin content of ~22 wt %), oleic acid, vaseline oil, vegetable oil, essential oil (in an amount of less than 5 wt %), and water are developed. The hydrodynamic diameter of t...

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Bibliographic Details
Published in:Nanobiotechnology Reports (Online) 2023-04, Vol.18 (2), p.283-289
Main Authors: Murashova, N. M., Trofimova, E. S., Gagueva, L. A.
Format: Article
Language:English
Subjects:
Chemical reactions
Chemistry and Materials Science
Cosmetics
Essential oils
Industrial and Production Engineering
Lecithin
Machines
Manufacturing
Materials Science
Microemulsions
Nanobiomedicine and Nanopharmaceutics
Nanotechnology
Oleic acid
Phase transitions
Phospholipids
Processes
Rhodamine
Vegetable oils
Water chemistry
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Summary:Reverse microemulsions for use in medicine and cosmetics in systems containing lecithin (a mixture of phospholipids with a lecithin content of ~22 wt %), oleic acid, vaseline oil, vegetable oil, essential oil (in an amount of less than 5 wt %), and water are developed. The hydrodynamic diameter of the droplets of the microemulsions ranges from 15 to 80 nm. The microemulsions are stable when heated up to 45°C: the mass loss is less than 1%, and no phase transitions and chemical reactions accompanied by the absorption or release of heat are observed. The microemulsions possess a delayed release of water-soluble substances: 3.6% water-soluble dye Rhodamine C is released from the microemulsion in 7 h of dialysis.
ISSN:2635-1676
1995-0780
2635-1684
1995-0799
DOI:10.1134/S2635167623700143