Role of phytoconstituents as natural α-amylase inhibitors: A review

Diabetes mellitus (DM) is the third leading cause of death in the world after cancer, heart disease, and stroke which is one of the most difficult diseases to treat today. Primary mellitus and its effects are expensive to treat, not only for people who have it, but also for health care systems aroun...

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Bibliographic Details
Main Authors: Saini, Nancy, Sirohi, Ritika, Kaur, Paranjeet, Wadhwa, Pankaj, Saini, Neetu, Sahu, Sanjeev Kumar
Format: Conference Proceeding
Language:English
Subjects:
Amylases
Diabetes
Diabetes mellitus
Digestion
Glucose
Health services
Heart diseases
Natural products
Natural resources
Pyrazole
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Summary:Diabetes mellitus (DM) is the third leading cause of death in the world after cancer, heart disease, and stroke which is one of the most difficult diseases to treat today. Primary mellitus and its effects are expensive to treat, not only for people who have it, but also for health care systems around the world. Amylase is involved in the digestion of starch, which is the main source of foreign glucose in the human diet. Prevention of amylase in the digestive tract to delay the absorption of glucose by delaying the digestion of starchy foods shows potency such as type II diabetes and / or treatment. Development of various anti-diabetic agents have been widely studied in recent decades. Natural products (NPs) have long been an important source of medicines, with the natural resources accounting for about half of the drugs currently used. Many natural products, especially those derived from plants, have been suggested for DM treatment. This review focused on bioactive phytoconstituents containing pyrazole ring target alpha amylase which exhibits the antidiabetic activity.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0168944