Phytochemical investigations, antioxidant activity & metal binding studies of ethanolic extract of pterospermum acerifolium roots

• Main Authors: Kumar, Jagdeep, Pundir, Mahima, Nishtha, Kumar, Akshay
• Format: Conference Proceeding
• Language: English
• Subjects: Antioxidants; Binding; Biosensors; Chemical compounds; Lead chlorides; Metabolites; Metal chlorides; Phytochemicals; Plant roots; Scavenging
• ISSN: 0094-243X; 1551-7616
• DOI: 10.1063/5.0140588

Traditional methods of developing drugs provide a vast source material for new drug development. Nowadays, natural plant products have been considered as a significant source of pharmacotherapeutics. From plants, a variety of chemical compounds can be isolated and can further be sorted according to their biosynthetic origin, chemical class, and functionality (primary and secondary metabolites). Considering this we have selected Pterospermum acerifolium plant to check for its metal binding properties and antioxidant values. Very less amount of work has been reported on this plant so the reason for selecting this plant for the exploration of medicinal aspects. The present study emphasizes on the preliminary phytochemical studies, antioxidant potential and metal binding activities of Pterospermum acerifolium roots. Binding potential and analysis of the extract of roots of Pterospermum acerifloium with various metal chlorides was carried by UV-Vis. spectrum. For this work, a comparative analysis was carried by calculating the absorption intensities of this plant root extract, metal chlorides and then the mixture of metal chloride with metal chloride at a suitable wavelength that ranged from 200 to 800 nm. Root extract of P. acerifolium showed the good potential for detecting Lead chlorides. This study can give future direction for detecting the various metal chlorides in water bodies and signifies that Pterospermum acerifolium has great potentials as biosensors. Antioxidant studies were carried on the roots of this plant at various concentrations ranging from 50, 100, 250, 500 µg/ mL and showed 94.32%, 95.6%, 97.37% and 98.69% radical scavenging which directed towards the medicinal potential of this plant. Further antioxidant property of Pterospermum acerifolium extract has been analysed with respect to Vitamin C, resulting a promising direction towards development of natural antioxidants.