Ultra‐Fast Photonic Digital Polymerase Chain Reaction based on N‐Heterocyclic Carbene Self‐Assembled Monolayer (Adv. Funct. Mater. 37/2023)

Photonic Digital PCRIn article number 2303728, Sang Hun Lee, Oh Seok Kwon, and co‐workers introduce a novel interfacial chemical, N‐Heterocyclic Carbene (NHC), for binding stability between Au and the anti‐quenching layer under high‐temperature based on the self‐assembled monolayer. This technology...

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Bibliographic Details
Published in:Advanced functional materials 2023-09, Vol.33 (37)
Main Authors: Kim, Kyung Ho, Seo, Sung Eun, Kim, Jinyeong, Park, Seon Joo, An, Jai Eun, Shin, Chan Jae, Ryu, Choong‐Min, Lee, Sung Woon, Nam, Ho Chul, Yoon, Tae Ho, Shin, Jong Cheol, Kim, Yu Kyung, Oh, Hanseul, Hong, Jung Joo, Kim, Brian N., Lee, Kyoung G., Song, Hyun Seok, Lee, Sang Hun, Kwon, Oh Seok
Format: Article
Language:English
Subjects:
Carbenes
Interface stability
Materials science
Monolayers
Photonics
Polymerase chain reaction
Quenching
Self-assembly
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Summary:Photonic Digital PCRIn article number 2303728, Sang Hun Lee, Oh Seok Kwon, and co‐workers introduce a novel interfacial chemical, N‐Heterocyclic Carbene (NHC), for binding stability between Au and the anti‐quenching layer under high‐temperature based on the self‐assembled monolayer. This technology overcomes the limitation of quenching issues in the plasmonic‐based digital polymerase chain reaction (dPCR) field. The novel interfacial chemical‐based photonic dPCR is promising for applications in the next PCR system and the molecular diagnosis field.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.202370219