Controllable Preparation of Monodisperse Chitosan Microspheres Based on Microfluidic Technology

Previous educational articles on microfluidic technology mainly focused on continuous microfluidics, so we set up an undergraduate laboratory experiment to introduce droplet microfluidics to students. Students can understand the concept of microfluidic channels and the principles of droplet microflu...

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Bibliographic Details
Published in:Journal of chemical education 2023-09, Vol.100 (9), p.3526-3532
Main Authors: Chen, Si-Ke, Ju, Xiao-Jie, Wei, Jie, Wang, Wei, Chu, Liang-Yin
Format: Article
Language:English
Subjects:
Chemistry
Chitosan
College students
Controllability
Droplets
Experiments
Microfluidics
Microspheres
Polydimethylsiloxane
Students
Teaching methods
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Summary:Previous educational articles on microfluidic technology mainly focused on continuous microfluidics, so we set up an undergraduate laboratory experiment to introduce droplet microfluidics to students. Students can understand the concept of microfluidic channels and the principles of droplet microfluidics, prepare polydimethylsiloxane (PDMS) devices and split-flow strategy, explore the controllable preparation and monodispersity of chitosan (CS) microspheres, and gain a more comprehensive understanding of microfluidic technology. The experiment has the advantages of easy operation and a short cycle, and it is suitable as an undergraduate experiment.
ISSN:0021-9584
1938-1328
DOI:10.1021/acs.jchemed.2c00901