68Ga-FAPi: Pathways and Diagnosis in Cardiac Imaging

Purpose of Review Myocardial fibrosis is a response to myocardial injury and plays a pivotal role in ventricular remodeling. Different patterns of fibrosis are associated with different disease states, but the presence and amount of fibrosis provide a different impact on prognosis. Recent Findings I...

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Bibliographic Details
Published in:Current cardiovascular imaging reports 2023-11, Vol.16 (11), p.93-101
Main Authors: Popescu, Cristina Elena, Ferro, Paola, Gotuzzo, Irene, Burger, Irene, Rominger, Axel, Caobelli, Federico
Format: Article
Language:English
Subjects:
Cardiology
Computed tomography
Diagnostic Radiology
Fibrosis
Imaging
Interventional Radiology
Medical imaging
Medicine
Medicine & Public Health
Nuclear Medicine
Positron emission
Radiology
Review
Topical Collection on Cardiac Nuclear Imaging
Ultrasound
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Summary:Purpose of Review Myocardial fibrosis is a response to myocardial injury and plays a pivotal role in ventricular remodeling. Different patterns of fibrosis are associated with different disease states, but the presence and amount of fibrosis provide a different impact on prognosis. Recent Findings In the latest years, fibroblast activation protein inhibitor (FAPi) positron emission tomography (PET) gain interest for its potential in detecting myocardial fibrosis, in differentiating between active and chronic disease, and in the assessment of disease progression and response to treatment. Summary We aim to highlight the most relevant current applications of FAPi PET/CT in cardiovascular imaging, focusing on its applications, advantages, limitations, and to underline future clinical perspective.
ISSN:1941-9066
1941-9074
DOI:10.1007/s12410-023-09583-3