C,N‐Diarylformamidines as Valuable Building Blocks in the Synthesis of Heterocyclic Compounds

Obtaining highly functionalized heterocyclic structures is an important topic of modern organic synthesis, as it reveals the possibility of constructing more complex systems and therefore, expanding the range of various drugs. Aiming at synthesizing complex molecules from simple and readily availabl...

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Bibliographic Details
Published in:European journal of organic chemistry 2023-10, Vol.26 (40), p.n/a
Main Authors: Trukhanova, Yulia A., Chernov, Nikita M., Kuvaeva, Elena V., Yakovlev, Igor P.
Format: Article
Language:English
Subjects:
amidines
C,N-diarylformamidines
Chemical synthesis
Complex systems
Heterocyclic compounds
heterocyclization
Reagents
synthesis
systematization
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Summary:Obtaining highly functionalized heterocyclic structures is an important topic of modern organic synthesis, as it reveals the possibility of constructing more complex systems and therefore, expanding the range of various drugs. Aiming at synthesizing complex molecules from simple and readily available reagents, the modification of C,N‐diarylformamidines, well known in medicinal chemistry, is of great interest. This article reviews comprehensively the field of C,N‐diarylformamidine chemistry and covers publications on this topic from 1999 to 2022. This review is devoted to the heterocyclization of C,N‐diarylformamidines and covers publications from 1999 to 2022. The comprehensive information collected enables other researchers to quickly understand the possibility of constructing various complex heterocycles from simple, readily available reagents.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.202300673