201TlCl production process in proton accelerator facility in nuclear energy research institute

In this manuscript, production of 201 TlCl, one of the radiopharmaceuticals used in the field of nuclear medicine for diagnostic purposes in heart, muscle, thyroid gland imaging, and cancer diagnosis, at Turkish Energy Nuclear and Mineral Research Agency is described. The production process starts w...

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Bibliographic Details
Published in:Journal of radioanalytical and nuclear chemistry 2023-11, Vol.332 (11), p.4687-4693
Main Author: Yıldız Akdag, Berna
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Cyclotrons
Diagnostic Radiology
Hadrons
Heavy Ions
Inorganic Chemistry
Nuclear Chemistry
Nuclear energy
Nuclear medicine
Nuclear Physics
Nuclear reactor components
Nuclear reactors
Physical Chemistry
Proton accelerators
Radiochemistry
Thyroid gland
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Summary:In this manuscript, production of 201 TlCl, one of the radiopharmaceuticals used in the field of nuclear medicine for diagnostic purposes in heart, muscle, thyroid gland imaging, and cancer diagnosis, at Turkish Energy Nuclear and Mineral Research Agency is described. The production process starts with a cyclotron type proton accelerator operated in energy range of 15–30 MeV with beam intensities up to 1200 μA currently available at the facility. The production is detailed along with the main lines in the other steps. In addition to the radiopharmaceutical productions carried out according to international standards at the facility, new projects are planned in the short and long terms.
ISSN:0236-5731
1588-2780
DOI:10.1007/s10967-023-08898-1