Content of polyphenolic compounds, flavonoids, antioxidant activity and antibacterial activity of Jatropha dioica hydroalcoholic extracts against Streptococcus mutans

Streptococcus mutans has been associated with the development of dental caries. Semidesert bush Jatropha dioica Sessé, found in northern Mexico and widely used as traditional medicine, is known to inhibit pathogenic bacteria. The Folin–Ciocalteu method and free radical capture by DPPH technique were...

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Published in:International journal of food science & technology 2023-12, Vol.58 (12), p.6736-6743
Main Authors: González‐Machado, Adriana Carolina, Torres‐León, Cristian, Castillo‐Maldonado, Irais, Delgadillo‐Guzmán, Dealmy, Hernández‐Morales, Cecilia, Flores‐Loyola, Erika, Marszalek, Jolanta E., Balagurusamy, Nagamani, del Carmen Vega‐Menchaca, María, Ascacio‐Valdés, Juan A., Pedroza‐Escobar, David, Ramírez‐Moreno, Agustina
Format: Article
Language:English
Subjects:
Antibacterial activity
Antimicrobial activity
Antioxidants
Bacteria
Dental caries
Flavonoids
Free radicals
Hydroxycinnamic acid
Jatropha dioica
Minimum inhibitory concentration
p-Hydroxybenzoic acid
Polyphenols
Streptococcus mutans
Toxicity
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Summary:Streptococcus mutans has been associated with the development of dental caries. Semidesert bush Jatropha dioica Sessé, found in northern Mexico and widely used as traditional medicine, is known to inhibit pathogenic bacteria. The Folin–Ciocalteu method and free radical capture by DPPH technique were used to determine total polyphenols (TP) and antioxidant activity (AA) respectively. The toxicity and antimicrobial activity of the extract with the highest TP and AA were determined. The highest value of TP (46.06 mg GAE g −1 ) was determined in the dried root extract. A significant and positive correlation was observed between TP and AA. In the flavonoid quantification, the extract showed the highest value of 4.57 mg QE g −1 . The hydroalcoholic extracts did not show toxicity. Hydroxycinnamic acid compounds and methoxyflavones and hydroxybenzoic acid were found in the extracts. These compounds are responsible for antibacterial activity. The minimum inhibitory concentration (MIC) against the Streptococcus mutans was found to be 3.75 mg mL −1 .
ISSN:0950-5423
1365-2621
DOI:10.1111/ijfs.16554