Adaptive Changes of Bowel in Rats with Various Length of Thiry-Vella Fistulas

[LANGUAGE= "English"] Purpose: The aim of the current experimental study was to determine interaction between functional and dysfunctional bowel segments in terms of structural changes in the gut mucosa.Materials and Methods: Twenty-two male rats were divided into four groups in which foll...

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Bibliographic Details
Published in:Journal of Clinical Practice & Research 2011-01, Vol.33 (3), p.205
Main Authors: Akçora, Bülent, Muhammed Enes Altuğ, Atik, Esin, Akansu, Bülent, Söğüt, Sadık
Format: Article
Language:English
Subjects:
Adaptation
Fistula
Small intestine
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Summary:[LANGUAGE= "English"] Purpose: The aim of the current experimental study was to determine interaction between functional and dysfunctional bowel segments in terms of structural changes in the gut mucosa.Materials and Methods: Twenty-two male rats were divided into four groups in which following operations were performed respectively: Group 1; sham operation, Group 2; 5% Thiry-Vella fistula, Group 3; 80% Thiry-Vella fistula, and Group 4; 5% Thiry-Vella fistula plus 75% bowel resection. At the end of the 14 days, ileum in continuity and Thiry-Vella fistula samples were examined histologically.Results: Mucosal thickness in ileal samples in continuity were 605±24 µ, 615±14 µ, 731±16 µ, 860±44 µ, in Groups 1, 2, 3 and 4, respectively. Group 3 and Group 4 were significantly different from other groups (p
ISSN:2980-2156