The antibacterial effect of bee venom on subclinical mastitis agents: an alternative for local treatment

Subclinical mastitis is an important problem in terms of the dairy economy all over the world and due to the increasing antibiotic resistance day by day, there is a great need for new antibiotic alternatives and natural products. The aim of this study is to examine the effectiveness of bee venom aga...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Applied Animal Research 2023-12, Vol.51 (1), p.323-332
Main Authors: Güven Gökmen, Tülin, Yazgan, Hatice, Sevin, Sedat, Turut, Nevin, Karahan, Şifa, Eşki, Funda, Kıvrak, İbrahim, Sezer, Osman, Erdem Ütük, Armağan
Format: Article
Language:English
Subjects:
Antibacterial activity
antibacterial effect
Antibiotic resistance
Antibiotics
bee venom
Mastitis
MIC
Mixed infection
Natural products
Subclinical mastitis
time-kill assay
Venom
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Subclinical mastitis is an important problem in terms of the dairy economy all over the world and due to the increasing antibiotic resistance day by day, there is a great need for new antibiotic alternatives and natural products. The aim of this study is to examine the effectiveness of bee venom against bacterial mastitis agents. Methods, such as well diffusion, disc diffusion, microdilution and time-kill analyses, were applied to 12 bacteria species isolated from milk samples. Effective results were obtained in microdilution and time-kill analysis. MIC values were determined in the range of 12.5-50 µg/ml and time-kill times were observed in the range of 1-24 h. In addition, bacterial suspensions from 12 species were prepared and there were effective against mixed infection in vitro. As a result, bee venom, as an antibiotic alternative, can give satisfactory results in the treatment of subclinical mastitis and mixed infections. Field studies and treatment trials should be emphasized.
ISSN:0971-2119
0974-1844
DOI:10.1080/09712119.2023.2197477