Childhood-Onset Systemic Lupus Erythematosus Presenting With Concomitant Gastrointestinal Manifestation and Antiphospholipid Syndrome

Childhood-onset systemic lupus erythematosus is a rare disease that is more prevalent in Southeast Asian children than in Western children. It is characterised by a peripubertal onset and a female predominance that rises with age. Haematological, renal, and mucocutaneous are among the frequently inv...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-11, Vol.15 (11)
Main Authors: Mohd Shukri, Nur Diyana, Wan Mohamad, Wan Majdiah, Wan Ab Rahman, Wan Suriana
Format: Article
Language:English
Subjects:
Abdomen
Anemia
Antibodies
Autoimmune diseases
Biopsy
Blood
Childhood
Disease
Enzymes
Fever
Glycoproteins
Hematology
Liver
Lupus
Medical screening
Pain
Pancreatitis
Patients
Proteins
Thrombocytopenia
Thrombosis
Ulcers
Ultrasonic imaging
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Summary:Childhood-onset systemic lupus erythematosus is a rare disease that is more prevalent in Southeast Asian children than in Western children. It is characterised by a peripubertal onset and a female predominance that rises with age. Haematological, renal, and mucocutaneous are among the frequently involved organs upon diagnosis. Some of the typical symptoms include cutaneous vasculitis, malar rash, and fever. Patients frequently had proliferative class IV lupus nephritis, which increases disease activity and kidney damage. We reported a child presented with fever associated with multiple joint pain, skin rashes over the fingers of the right hand, and generalised abdominal pain.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.49205