Imunocromatografic Tests Improving Point-of-Care Management of Respiratory Virus Infection in Children

Background: Respiratory syncytial virus (RSV) and influenza virus (flu) contribute substantially to the overall burden of severe respiratory tract infection in children. However, the molecular etiological diagnostic methods of viral infection are still insufficiently accessible in public hospitals....

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Published in:Infection control and hospital epidemiology 2020-10, Vol.41 (S1), p.s291-s291
Main Authors: Mendes, Elisa Teixeira, Paranhos, Hadassa Louback, Santos, Isabela Cristina Moreira, Barbosa, Nathália Reis Sartori, da Silva, Raquel Vieira, Lima, Maria Patelli Juliani Souza
Format: Article
Language:English
Subjects:
Antibiotics
Disease control
Epidemics
Hospitals
Infections
Influenza
Multivariate analysis
Observational studies
Respiratory diseases
Respiratory syncytial virus
Respiratory tract
Viral infections
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Summary:Background: Respiratory syncytial virus (RSV) and influenza virus (flu) contribute substantially to the overall burden of severe respiratory tract infection in children. However, the molecular etiological diagnostic methods of viral infection are still insufficiently accessible in public hospitals. Rapid immunochromatographic tests can add important information at the point of care, including antiviral or antibiotic indication, viral , and effective precaution measures to prevent outbreaks. The aim of this study was to evaluate this impact for pediatric patients under 5 years of age in our hospital. Methods: We conducted a retrospective, observational study of clinical outcomes of children under 5 years requiring hospitalization from 2013 to 2018 for viral respiratory disease, and who had positive RSV and/or flu immunochromatographic rapid test results. Results: In total, we identified 221 cases: RSV, 193; flu, 6; codetections, 19. (Table 1). The mortality rate was 1.8% (2 cases), and 88% of our patients were
ISSN:0899-823X
1559-6834
DOI:10.1017/ice.2020.866