Thermo-mechanical stability and antibacterial activity of merwinite derived from different fuels

• Published in: Journal of materials research 2023-12, Vol.38 (23), p.5045-5054
• Main Authors: Collin, Samuel M, Augustine, Joel, Abraham, Jayanthi, Sasikumar, S.
• Format: Article
• Language: English
• Subjects: Applied and Technical Physics; Biomaterials; Biomedical materials; Body fluids; Chemistry and Materials Science; Citric acid; Coliforms; Compressive strength; Differential thermal analysis; Dilution; E coli; Fuels; Fungicides; Fusarium oxysporum; Glycine; In vitro methods and tests; Inorganic Chemistry; Materials Engineering; Materials research; Materials Science; Merwinite; Nanotechnology; Nucleation; Ureas
• ISSN: 0884-2914; 2044-5326
• DOI: 10.1557/s43578-023-01215-2

Merwinite synthesized using different fuels were characterised using TGA-DTA, FTIR, SEM/EDX, and TEM/EDX. In vitro biomineralisation assay using simulated body fluid (SBF) as the mineralisation medium showed that both glycine and citric acid sets exhibited good HAp nucleation ability, with glycine sets showing higher degree of HAp nucleation. Mechanical studies demonstrated that glycine sets had the highest mechanical strength, with a compressive strength of 40 MPa compared to 30 MPa for citric acid sets and 20 MPa for urea sets. Antibacterial studies and antifungal assays were performed using the disk diffusion method and broth dilution technique against bacteria Escherichia coli , Staphylococcus aureus , and fungi Aspergillus niger and Fusarium oxysporum . Results showed that glycine sets had highest antibacterial activity against E. coli and S. aureus , with inhibition zone diameters of 25 mm and 20 mm, respectively, while urea sets exhibited lower antibacterial activity. Graphical abstract