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Synthesis of Enantiopure Chiral Perhydrobenzimidazole and Hexahydroquinoxaline Derivatives

Starting from 2-anilino-2-ethoxy-3-oxothiobutyric acid anilides and (R, R)-or (S, S)-trans-1,2-diaminocyclohexane, chiral C2-disubstituted perhydrobenzimidazole and trans-4a,5,6,7,8,8a-hexahydroquinoxaline derivatives were obtained depending on the polarity of the solvent.

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Published in:Monatshefte für Chemie 2000-10, Vol.131 (10), p.1061-1066
Main Authors: Zaleska, Barbara, Socha, Robert
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Language:English
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Socha, Robert
description Starting from 2-anilino-2-ethoxy-3-oxothiobutyric acid anilides and (R, R)-or (S, S)-trans-1,2-diaminocyclohexane, chiral C2-disubstituted perhydrobenzimidazole and trans-4a,5,6,7,8,8a-hexahydroquinoxaline derivatives were obtained depending on the polarity of the solvent.
doi_str_mv 10.1007/s007060070038
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title Synthesis of Enantiopure Chiral Perhydrobenzimidazole and Hexahydroquinoxaline Derivatives
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