Calciphylaxis: An Unusual and Silent Usher for an Underlying Carcinoma

Calciphylaxis is an uncommon but serious and potentially life-threatening painful condition that is characterized by cutaneous vascular calcification and ischemia. It is typically seen in patients with end-stage renal disease but has been known to occur less commonly in patients with normal renal fu...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-11, Vol.15 (11), p.e48363
Main Authors: Vijaya Prakash, Aviraag, Srinivasan Kumar, Madhan, Veulens, Jessica
Format: Article
Language:English
Subjects:
Abdomen
Anticoagulants
Biopsy
Calcification
Coronaviruses
COVID-19
Kidney diseases
Liver cancer
Liver cirrhosis
Medical diagnosis
Pain
Pathogenesis
Patients
Proteins
Skin
Smooth muscle
Thrombosis
Tumor necrosis factor-TNF
Ulcers
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Summary:Calciphylaxis is an uncommon but serious and potentially life-threatening painful condition that is characterized by cutaneous vascular calcification and ischemia. It is typically seen in patients with end-stage renal disease but has been known to occur less commonly in patients with normal renal function. A rare but established etiology of non-uremic calciphylaxis is malignancy. We have thus far been successful in documenting an association between calciphylaxis and certain solid tumor types. The objective of this clinical case study is to better define a possible association between calciphylaxis and underlying malignancy.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.48363