Walsh coefficients and circuits for several alleles

Walsh coefficients have been applied extensively to biallelic systems for quantifying pairwise and higher order epistasis, in particular for demonstrating the empirical importance of higher order interactions. Circuits, or minimal dependence relations, and related approaches that use triangulations...

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Bibliographic Details
Published in:arXiv.org 2024-01
Main Authors: Crona, Kristina, Greene, Devin
Format: Article
Language:English
Subjects:
Circuits
Coefficients
Polytopes
Online Access:Get full text
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Summary:Walsh coefficients have been applied extensively to biallelic systems for quantifying pairwise and higher order epistasis, in particular for demonstrating the empirical importance of higher order interactions. Circuits, or minimal dependence relations, and related approaches that use triangulations of polytopes have also been applied to biallelic systems. Here we provide biological interpretations of Walsh coefficients for several alleles, and discuss circuits in the same general setting.
ISSN:2331-8422