A Review On Herbal Medicines As Neuroprotective Agent

• Published in: International journal of public mental health and neurosciences 2021-04, Vol.8 (1), p.1-7
• Main Authors: Prathiba, H D, Karigar, Chandrakant S
• Format: Article
• Language: English
• Subjects: Herbal medicine; Neurodegeneration; Parkinson's disease; Pathology; Pharmaceuticals
• ISSN: 2394-4668

Herbal medicines make up a significant component of the trend toward alternative medicine. Herbal medicine is becoming ever more popular in today's world as people seek out natural remedies. Herbal medicines have been used since the dawn of civilization to maintain health and to treat various diseases. Neurodegeneration refers to any pathological condition in which the nervous system or neuron loses its function, structure, or both. Neuronal death happening as a result of progressive disease of long-term and is becoming a major health problem in the 21st century. Many neurodegenerative diseases are caused by genetic mutations, most of which are located in completely unrelated genes. In many of the different diseases neurons degenerated are not changed resulting in a cognitive loss, many neurodegenerative disorders, such as Alzheimer's disease, cerebrovascular impairment, seizure disorders, head injury, parkinsonism. The common pathology of neurodegeneration includes deposition of misfolded proteins such as amyloid-ß in Alzheimer's disease, α-synuclein in Parkinson's disease, Neuroprotection refers to the ability for a therapy to prevent neuronal cell death by intervening in and inhibiting the pathogenetic cascade that are able to protect the central nervous system against neuronal injury and neurodegenerative disorders. The past decade has viewed an intense interest in herbal plants having long-term health-promoting or medicinal qualities. To compete with the growing pharmaceutical market, there is an importance to use and scientifically authenticate more medicinally useful herbal products. Comprehensive research and discovery have demonstrated that natural products, medicinal herbs, plant extracts, and their metabolites, have great potential as the neuroprotective agent. Thus the herbal plants can be aappreciated source of the drug against neurodegenerative disorders which will require high-throughput screening. This review will provides a general idea of herbal plants and their phytoconstituents against neurodegenerative infections and other related disorders, focusing on their mechanism of action and therapeutic potential.