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P16 Case description of myositis-peritonitis(FASCIITIS) in a 4 year old female toddler who was hospitalised in our clinic

BackgroundMyofasciitis is a rare disease of the muscles and its fascia, which is most common in adults and is very rarely found in children.AimDescription of a case of myositis-peritonitis(fasciitis) in a 4 year old female toddler and arise the awareness of the hospital and general paediatrician for...

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Published in:Archives of disease in childhood 2017-06, Vol.102 (Suppl 2), p.A40-A41
Main Authors: Vlachopoulos, Vasileios, Tsikrikas, Theodoros, Papakyritsi, Dimitra, Velali, Kyriaki N, Gianniki, Maria G, Bampalitsa, Sofia-Dimitra, Atmatzidou, Eleni, Sarigianni, Maria, Tsakos, Konstantinos, Vatidis, Dimos, Anastasiou-Katsiardani, Anastasia
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container_end_page A41
container_issue Suppl 2
container_start_page A40
container_title Archives of disease in childhood
container_volume 102
creator Vlachopoulos, Vasileios
Tsikrikas, Theodoros
Papakyritsi, Dimitra
Velali, Kyriaki N
Gianniki, Maria G
Bampalitsa, Sofia-Dimitra
Atmatzidou, Eleni
Sarigianni, Maria
Tsakos, Konstantinos
Vatidis, Dimos
Anastasiou-Katsiardani, Anastasia
description BackgroundMyofasciitis is a rare disease of the muscles and its fascia, which is most common in adults and is very rarely found in children.AimDescription of a case of myositis-peritonitis(fasciitis) in a 4 year old female toddler and arise the awareness of the hospital and general paediatrician for the clinical presentation of this rare disease.Method-material-case descriptionIn November of 2016 a 4 year old toddler of greek origin from the state of Magnesia, Greece, was admitted to the emergency department of our hospital. The toddler presented claudication 12 hours prior to the admission and symptoms of upper and lower respiratory tract infection with cough from several days. At the admission the toddler presented claudication, limitation of the active and passive motility of both hips, especially the right, limited motility of the truncus and limbs, swelling of right cheek and right temple. Imaging studies revealed swelling of the soft tissues around the right hip joint and swelling of multiple intra-parotid and neck lymph nodes. The blood examination at the admission revealed leukocytosis, mild increase of the indicators of inflammation, of creatine phosphokinase (CPK) and increased coagulation time. Because of the clinical picture of the patient intravenous antibiotics were givenB(ceftriaxone and clindamycin).The differential diagnosis included myositis, fasciitis, septic arthritis of right hip joint and invasive general microbe infection.ResultsBecause of the rapid deterioration of the clinical and laboratory picture in the next 12 hours (further increase of CPK, indicators of inflammation) the toddler was transferred to a tertiary Hospital of Athens. The imaging studies revealed a consolidation of the basis of the right lung and mild consolidation behind the heart. The MRI revealed swelling and inflammation of the majority of the muscles of the haunches, the thighs (especially the right), swelling of the subcutaneous tissue of both haunches and its fascias. The clinical and imaging picture was compatible with myofasciitis. The general status of the patient was improved and the antibiotic therapy was continued for 14 days in total. The metabolic and rheumatologic results are still pending.ConclusionsThe data in literature for myofasiitis are not enough but we believe that it is localised histological inflammation that may be caused by a previous immunisation with alluminium adjuvants contained vaccines, rather than a primary inflammatory muscle dise
doi_str_mv 10.1136/archdischild-2017-313273.104
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The toddler presented claudication 12 hours prior to the admission and symptoms of upper and lower respiratory tract infection with cough from several days. At the admission the toddler presented claudication, limitation of the active and passive motility of both hips, especially the right, limited motility of the truncus and limbs, swelling of right cheek and right temple. Imaging studies revealed swelling of the soft tissues around the right hip joint and swelling of multiple intra-parotid and neck lymph nodes. The blood examination at the admission revealed leukocytosis, mild increase of the indicators of inflammation, of creatine phosphokinase (CPK) and increased coagulation time. Because of the clinical picture of the patient intravenous antibiotics were givenB(ceftriaxone and clindamycin).The differential diagnosis included myositis, fasciitis, septic arthritis of right hip joint and invasive general microbe infection.ResultsBecause of the rapid deterioration of the clinical and laboratory picture in the next 12 hours (further increase of CPK, indicators of inflammation) the toddler was transferred to a tertiary Hospital of Athens. The imaging studies revealed a consolidation of the basis of the right lung and mild consolidation behind the heart. The MRI revealed swelling and inflammation of the majority of the muscles of the haunches, the thighs (especially the right), swelling of the subcutaneous tissue of both haunches and its fascias. The clinical and imaging picture was compatible with myofasciitis. The general status of the patient was improved and the antibiotic therapy was continued for 14 days in total. The metabolic and rheumatologic results are still pending.ConclusionsThe data in literature for myofasiitis are not enough but we believe that it is localised histological inflammation that may be caused by a previous immunisation with alluminium adjuvants contained vaccines, rather than a primary inflammatory muscle disease. The histological hallmark of myofasciitis is the infiltration of the muscle and its fascia by macrophage cells. The symptoms include joint pain, muscle weakness, fatigue, fever and pain on the palpation of the muscles.</description><identifier>ISSN: 0003-9888</identifier><identifier>EISSN: 1468-2044</identifier><identifier>DOI: 10.1136/archdischild-2017-313273.104</identifier><identifier>CODEN: ADCHAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group LTD</publisher><subject>Adjuvants ; Antibiotics ; Cardiovascular diseases ; Ceftriaxone ; Cheek ; Clindamycin ; Cough ; Creatine ; Creatine kinase ; Differential diagnosis ; Emergency medical care ; Fascia ; Fasciitis ; Hip ; Hip joint ; Hospitals ; Immunization ; Inflammation ; Inflammatory diseases ; Leukocytosis ; Lymph nodes ; Macrophages ; Motility ; Muscles ; Musculoskeletal diseases ; Myositis ; Pain ; Patients ; Pediatrics ; Peritonitis ; Rare diseases ; Respiratory tract ; Soft tissues ; Toddlers ; Young Children</subject><ispartof>Archives of disease in childhood, 2017-06, Vol.102 (Suppl 2), p.A40-A41</ispartof><rights>2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>Copyright: 2017 (c) 2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>2017 2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2913030844/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2913030844?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,776,780,21358,21374,27903,27904,33590,33856,43712,43859,73967,74143</link.rule.ids></links><search><creatorcontrib>Vlachopoulos, Vasileios</creatorcontrib><creatorcontrib>Tsikrikas, Theodoros</creatorcontrib><creatorcontrib>Papakyritsi, Dimitra</creatorcontrib><creatorcontrib>Velali, Kyriaki N</creatorcontrib><creatorcontrib>Gianniki, Maria G</creatorcontrib><creatorcontrib>Bampalitsa, Sofia-Dimitra</creatorcontrib><creatorcontrib>Atmatzidou, Eleni</creatorcontrib><creatorcontrib>Sarigianni, Maria</creatorcontrib><creatorcontrib>Tsakos, Konstantinos</creatorcontrib><creatorcontrib>Vatidis, Dimos</creatorcontrib><creatorcontrib>Anastasiou-Katsiardani, Anastasia</creatorcontrib><title>P16 Case description of myositis-peritonitis(FASCIITIS) in a 4 year old female toddler who was hospitalised in our clinic</title><title>Archives of disease in childhood</title><description>BackgroundMyofasciitis is a rare disease of the muscles and its fascia, which is most common in adults and is very rarely found in children.AimDescription of a case of myositis-peritonitis(fasciitis) in a 4 year old female toddler and arise the awareness of the hospital and general paediatrician for the clinical presentation of this rare disease.Method-material-case descriptionIn November of 2016 a 4 year old toddler of greek origin from the state of Magnesia, Greece, was admitted to the emergency department of our hospital. The toddler presented claudication 12 hours prior to the admission and symptoms of upper and lower respiratory tract infection with cough from several days. At the admission the toddler presented claudication, limitation of the active and passive motility of both hips, especially the right, limited motility of the truncus and limbs, swelling of right cheek and right temple. Imaging studies revealed swelling of the soft tissues around the right hip joint and swelling of multiple intra-parotid and neck lymph nodes. The blood examination at the admission revealed leukocytosis, mild increase of the indicators of inflammation, of creatine phosphokinase (CPK) and increased coagulation time. Because of the clinical picture of the patient intravenous antibiotics were givenB(ceftriaxone and clindamycin).The differential diagnosis included myositis, fasciitis, septic arthritis of right hip joint and invasive general microbe infection.ResultsBecause of the rapid deterioration of the clinical and laboratory picture in the next 12 hours (further increase of CPK, indicators of inflammation) the toddler was transferred to a tertiary Hospital of Athens. The imaging studies revealed a consolidation of the basis of the right lung and mild consolidation behind the heart. The MRI revealed swelling and inflammation of the majority of the muscles of the haunches, the thighs (especially the right), swelling of the subcutaneous tissue of both haunches and its fascias. The clinical and imaging picture was compatible with myofasciitis. The general status of the patient was improved and the antibiotic therapy was continued for 14 days in total. The metabolic and rheumatologic results are still pending.ConclusionsThe data in literature for myofasiitis are not enough but we believe that it is localised histological inflammation that may be caused by a previous immunisation with alluminium adjuvants contained vaccines, rather than a primary inflammatory muscle disease. The histological hallmark of myofasciitis is the infiltration of the muscle and its fascia by macrophage cells. The symptoms include joint pain, muscle weakness, fatigue, fever and pain on the palpation of the muscles.</description><subject>Adjuvants</subject><subject>Antibiotics</subject><subject>Cardiovascular diseases</subject><subject>Ceftriaxone</subject><subject>Cheek</subject><subject>Clindamycin</subject><subject>Cough</subject><subject>Creatine</subject><subject>Creatine kinase</subject><subject>Differential diagnosis</subject><subject>Emergency medical care</subject><subject>Fascia</subject><subject>Fasciitis</subject><subject>Hip</subject><subject>Hip joint</subject><subject>Hospitals</subject><subject>Immunization</subject><subject>Inflammation</subject><subject>Inflammatory diseases</subject><subject>Leukocytosis</subject><subject>Lymph nodes</subject><subject>Macrophages</subject><subject>Motility</subject><subject>Muscles</subject><subject>Musculoskeletal diseases</subject><subject>Myositis</subject><subject>Pain</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>Peritonitis</subject><subject>Rare diseases</subject><subject>Respiratory tract</subject><subject>Soft tissues</subject><subject>Toddlers</subject><subject>Young Children</subject><issn>0003-9888</issn><issn>1468-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>ALSLI</sourceid><sourceid>CJNVE</sourceid><sourceid>M0P</sourceid><recordid>eNp9kU9LwzAUwIMoOKffIaAHPXQmfWmaHMdwOhgobJ5LmqQso2tq0iHDixe_qJ_Elnnw5Ok9Hr_3jx9CN5RMKAV-r4LeGBf1xtUmSQnNE6CQ5jChhJ2gEWVc9GXGTtGIEAKJFEKco4sYt4TQVAgYoY8Xyr8_v2YqWmxs1MG1nfMN9hXeHXx0nYtJa4PrfDPkt_PparZYrBerO-warDDDB6sC9rXBld2p2uLOG1PbgN83Hr-riDc-tq5TtYvWDD1-H7CuXeP0JTqrVB3t1W8co9f5w3r2lCyfHxez6TIp-z9YQnOQYLkiuaykUlVpVaVpKbLcyIxpI3kmUjA60was5VrwrKK5YZIyJivDYIyuj3Pb4N_2NnbFtj-i6VcWqaRAgAj2L0Ul4cAkQNpT-ZEqd9uiDW6nwqGgpBh8FH99FIOP4uijBxj8AAzpglE</recordid><startdate>201706</startdate><enddate>201706</enddate><creator>Vlachopoulos, Vasileios</creator><creator>Tsikrikas, Theodoros</creator><creator>Papakyritsi, Dimitra</creator><creator>Velali, Kyriaki N</creator><creator>Gianniki, Maria G</creator><creator>Bampalitsa, Sofia-Dimitra</creator><creator>Atmatzidou, Eleni</creator><creator>Sarigianni, Maria</creator><creator>Tsakos, Konstantinos</creator><creator>Vatidis, Dimos</creator><creator>Anastasiou-Katsiardani, Anastasia</creator><general>BMJ Publishing Group LTD</general><scope>0-V</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88B</scope><scope>88E</scope><scope>88I</scope><scope>8A4</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>CJNVE</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0P</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEDU</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope></search><sort><creationdate>201706</creationdate><title>P16 Case description of myositis-peritonitis(FASCIITIS) in a 4 year old female toddler who was hospitalised in our clinic</title><author>Vlachopoulos, Vasileios ; 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The toddler presented claudication 12 hours prior to the admission and symptoms of upper and lower respiratory tract infection with cough from several days. At the admission the toddler presented claudication, limitation of the active and passive motility of both hips, especially the right, limited motility of the truncus and limbs, swelling of right cheek and right temple. Imaging studies revealed swelling of the soft tissues around the right hip joint and swelling of multiple intra-parotid and neck lymph nodes. The blood examination at the admission revealed leukocytosis, mild increase of the indicators of inflammation, of creatine phosphokinase (CPK) and increased coagulation time. Because of the clinical picture of the patient intravenous antibiotics were givenB(ceftriaxone and clindamycin).The differential diagnosis included myositis, fasciitis, septic arthritis of right hip joint and invasive general microbe infection.ResultsBecause of the rapid deterioration of the clinical and laboratory picture in the next 12 hours (further increase of CPK, indicators of inflammation) the toddler was transferred to a tertiary Hospital of Athens. The imaging studies revealed a consolidation of the basis of the right lung and mild consolidation behind the heart. The MRI revealed swelling and inflammation of the majority of the muscles of the haunches, the thighs (especially the right), swelling of the subcutaneous tissue of both haunches and its fascias. The clinical and imaging picture was compatible with myofasciitis. The general status of the patient was improved and the antibiotic therapy was continued for 14 days in total. The metabolic and rheumatologic results are still pending.ConclusionsThe data in literature for myofasiitis are not enough but we believe that it is localised histological inflammation that may be caused by a previous immunisation with alluminium adjuvants contained vaccines, rather than a primary inflammatory muscle disease. The histological hallmark of myofasciitis is the infiltration of the muscle and its fascia by macrophage cells. The symptoms include joint pain, muscle weakness, fatigue, fever and pain on the palpation of the muscles.</abstract><cop>London</cop><pub>BMJ Publishing Group LTD</pub><doi>10.1136/archdischild-2017-313273.104</doi></addata></record>
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subjects Adjuvants
Antibiotics
Cardiovascular diseases
Ceftriaxone
Cheek
Clindamycin
Cough
Creatine
Creatine kinase
Differential diagnosis
Emergency medical care
Fascia
Fasciitis
Hip
Hip joint
Hospitals
Immunization
Inflammation
Inflammatory diseases
Leukocytosis
Lymph nodes
Macrophages
Motility
Muscles
Musculoskeletal diseases
Myositis
Pain
Patients
Pediatrics
Peritonitis
Rare diseases
Respiratory tract
Soft tissues
Toddlers
Young Children
title P16 Case description of myositis-peritonitis(FASCIITIS) in a 4 year old female toddler who was hospitalised in our clinic
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