A promising electrochemical sensor based on PVP-induced shape control of a hydrothermally synthesized layered structured vanadium disulfide for the sensitive detection of a sulfamethoxazole antibiotic

• Published in: Analyst (London) 2024-01, Vol.149 (2), p.386-394
• Main Authors: Shi, Mingjiao, Shi, Peizheng, Yang, Xinxin, Zhao, Ningbin, Wu, Mengfan, Li, Jing, Ye, Chen, Li, He, Jiang, Nan, Li, Xiufen, Lai, Guosong, Xie, Wan-Feng, Fu, Li, Wang, Gang, Zhu, Yangguang, Tsai, Hsu-Sheng, Lin, Cheng-Te
• Format: Article
• Language: English
• Subjects: Antibiotics; Chemical sensors; Composite materials; Ecological effects; Electrodes; Sensors; Shape control
• ISSN: 0003-2654; 1364-5528
• DOI: 10.1039/d3an01355c

The presence of sulfamethoxazole (SMX) in natural waters has become a significant concern recently because of its detrimental effects on human health and the ecological environment. To address this issue, it is of utmost urgency to develop a reliable method that can determine SMX at ultra-low levels. In our research, we utilized PVP-induced shape control of a hydrothermal synthesis method to fabricate layer-like structured VS 2 , and employed it as an electrode modification material to prepare an electrochemical sensor for the sensitive determination of SMX. Thus, our prepared VS 2 electrodes exhibited a linear range of 0.06-10.0 μM and a limit of detection (LOD) as low as 47.0 nM (S/N = 3) towards SMX detection. Additionally, the electrochemical sensor presented good agreement with the HPLC method, and afforded perfect recovery results (97.4-106.8%) in the practical analysis. The results validated the detection accuracy of VS 2 electrodes, and demonstrated their successful applicability toward the sensitive determination of SMX in natural waters. In conclusion, this research provides a promising approach for the development of electrochemical sensors based on VS 2 composite materials. Layer-like structured VS 2 was fabricated by a PVP-assisted hydrothermal synthesis method, and was modified on glassy carbon electrodes as the SMX sensors. The proposed SMX sensors exhibited a detection limit of 47.0 nM and afforded good recovery results of 97.4-106.8% in the practical analysis.