EPR Detection of Iron Storage in Rat Tissues After Simulated Microgravity Model

By a method of spectroscopy of electron paramagnetic resonance the tissues of rats after exposure of microgravity simulation (model of hindlimb unloading) were investigated. In the tissues of heart, lung, liver and muscles the signals of electron magnetic resonance (EMR) depending on orientation wer...

Full description

Saved in:
Bibliographic Details
Published in:Applied magnetic resonance 2016-06, Vol.47 (6), p.555-565
Main Authors: Yurtaeva, S. V., Efimov, V. N., Yafarova, G. G., Eremeev, A. A., Iyudin, V. S., Rodionov, A. A., Gainutdinov, Kh. L., Yatsyk, I. V.
Format: Article
Language:English
Subjects:
Accumulation
Aerospace medicine
Anisotropy
Atoms and Molecules in Strong Fields
Atrophy
Dependence
Electron paramagnetic resonance
Iron
Laser Matter Interaction
Magnetic fields
Magnetite
Metabolism
Microgravity
Nanoparticles
Nitrogen
Organic Chemistry
Organisms
Physical Chemistry
Physics
Physics and Astronomy
Physiology
Proteins
Simulation
Solid State Physics
Spectroscopy/Spectrometry
Spectrum analysis
Tissues
Weightlessness
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:By a method of spectroscopy of electron paramagnetic resonance the tissues of rats after exposure of microgravity simulation (model of hindlimb unloading) were investigated. In the tissues of heart, lung, liver and muscles the signals of electron magnetic resonance (EMR) depending on orientation were detected. The temperature and orientation dependences of the signals were studied. Comprehensive analysis of the characteristics of the EMR signals made it possible to identify the source of the signals as a crystalline magnetite. Three types of anisotropic EMR signals corresponding to a variety of spatial forms of accumulation of biogenic magnetite were detected. The appearance of the signals after microgravity simulation indicates an alteration in iron metabolism and an abnormal accumulation of iron in the rat tissues.
ISSN:0937-9347
1613-7507
DOI:10.1007/s00723-016-0779-3