The function of hemodialysis equipment in bioengineered systems for artificial clearance of blood

Conclusions1. A mathematical model of the content of electrolytes, low- and moderate-molecular-weight organic metabolic products, and liquid in the healthy human body and in the human body in various pathologic states was constructed.2. During artificial clearance, the human body, operator, and cont...

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Bibliographic Details
Published in:Biomedical engineering 1999-03, Vol.33 (2), p.61-66
Main Author: Grinval'd, V. M.
Format: Article
Language:English
Subjects:
Artificial organs
Bioengineering
Biotechnology
Blood
Control equipment
Controllability
Electrolytes
Hemodialysis
Human body
Mathematical analysis
Mathematical models
Operators (mathematics)
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Summary:Conclusions1. A mathematical model of the content of electrolytes, low- and moderate-molecular-weight organic metabolic products, and liquid in the healthy human body and in the human body in various pathologic states was constructed.2. During artificial clearance, the human body, operator, and control and diagnosis equipment constitute a biotechnical system of artificial clearance.3. Extracorporeal artificial clearance is performed using extracorporeal artificial organs, each of them consisting of a control element and an executive element. The control element uses input information to generate control medium. In the executive element, the control medium either directly or through artificial membranes affects the controllable medium of the organism. In the general case, the products of the interaction between these media produce a draining system which can be used in the control element to obtain diagnostic information on the condition of the patient and the artificial clearance procedure.4. A model for the structure of a biotechnical hemodialysis system based on extracorporeal artificial organs is proposed.5. Hemodialysis equipment is used as a temporary or permanent replacement for the excretory function of the natural kidney. The material-energy medium (dialyzate) used for hemodialysis has a substantial effect on the patient's blood.6. A mathematical description of the requirements imposed on the functions of a biotechnical hemodialysis system is proposed.
ISSN:0006-3398
1573-8256
DOI:10.1007/BF02386170