Effect of blood oxygenation on proton NMR signal shape

Conclusions1. The NMR signal width of blood protons is determined by symmetric broadening caused by dipoledipole interaction of blood plasma protons and asymmetric broadening caused by erythrocytes.2. The signal broadening caused by erythrocytes is determined by deviation of the cell shape from sphe...

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Bibliographic Details
Published in:Biomedical engineering 2000-01, Vol.34 (1), p.1-4
Main Authors: Zhernovoi, A. I., Sharshina, L. M.
Format: Article
Language:English
Subjects:
Blood
Blood plasma
Cell size
Erythrocytes
Frequency shift
NMR
Nuclear magnetic resonance
Oxygenation
Protons
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Summary:Conclusions1. The NMR signal width of blood protons is determined by symmetric broadening caused by dipoledipole interaction of blood plasma protons and asymmetric broadening caused by erythrocytes.2. The signal broadening caused by erythrocytes is determined by deviation of the cell shape from spherical, and it increases linearly as the degree of blood oxygenation decreases.3. The NMR signal width can be used for determining the degree of blood oxygenation, whereas the width to the resonance frequency shift ratio can provide information about erythrocyte shape.
ISSN:0006-3398
1573-8256
DOI:10.1007/BF02385217