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Facile Green Synthesis of SnO2 NPs Using Vitex altissima (L.) Leaves Extracts: Characterization and Evaluation of Antibacterial and Anticancer Properties

An eco-friendly approach is introduced for the synthesis of SnO 2 nanoparticles using the Vitex altissima L. plant extract. Bioinspired mediated synthesis of nanoparticles have been suggested as a very simple, inexpensive, non-toxic and environmental manner. The presence of biomolecules in V. altiss...

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Bibliographic Details
Published in:Journal of cluster science 2019-03, Vol.30 (2), p.431-437
Main Authors: Bhavana, S., Gubbiveeranna, Vinod, Kusuma, C. G., Ravikumar, H., Sumachirayu, C. K., Nagabhushana, H., Nagaraju, S.
Format: Article
Language:English
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Summary:An eco-friendly approach is introduced for the synthesis of SnO 2 nanoparticles using the Vitex altissima L. plant extract. Bioinspired mediated synthesis of nanoparticles have been suggested as a very simple, inexpensive, non-toxic and environmental manner. The presence of biomolecules in V. altissima induced the metal salts to form metal oxides. The prepared SnO 2 NPs were characterized by XRD, UV–Vis, FT-IR, SEM and TEM Techniques. The PXRD patterns revealed that SnO 2 nanoparticles exhibits tetragonal structure and its average crystallite size of SnO 2 NPs is found in the range of ~ 10 to 20 nm. The UV–visible absorption spectrum of SnO 2 nanoparticles showed absorption band at 257 nm and its band gap was found to be 4.18 eV. FTIR spectrum of green synthesized SnO 2 NPs shows the band at 534.22 cm −1 which indicates O–Sn–O stretching vibration modes. The morphological features of SnO 2 nanoparticles were fundamentally dependent up on concentration of V. altissima leaves extract. Green synthesized SnO 2 nanoparticles exhibit significant antibacterial activity against pathogenic bacterial strains by agar well diffusion method. Furthermore, the SnO 2 NPs shows significant cytotoxic effect on MCF-7 cancerous cell line. This result indicates that, V. altissima leaves extract acts as a reducing agent for the formations of SnO 2 NPs with effective biological properties.
ISSN:1040-7278
1572-8862
DOI:10.1007/s10876-019-01496-w