Microwave Assisted Biosynthesis of Cadmium Nanoparticles: Characterization, Antioxidant and Cytotoxicity Studies

• Published in: Journal of cluster science 2022-09, Vol.33 (5), p.1877-1887
• Main Authors: Shakibaie, Mojtaba, Riahi-Madvar, Soudabe, Ameri, Atefeh, Amiri-Moghadam, Parinaz, Adeli-Sardou, Mahboubeh, Forootanfar, Hamid
• Format: Article
• Language: English
• Subjects: Acids; Antioxidants; Aqueous solutions; Ascorbic acid; Bacteria; Biosynthesis; Cadmium; Catalysis; Chemistry; Chemistry and Materials Science; Energy consumption; Flavonoids; Gram-positive bacteria; Inorganic Chemistry; Microwaves; Nanochemistry; Nanoparticles; Nitrates; Original Paper; Physical Chemistry; Potassium; Radiation; Scavenging; Toxicity
• ISSN: 1040-7278; 1572-8862
• DOI: 10.1007/s10876-021-02107-3

The main aim of this study was to determine physicochemical, antioxidant, and cytotoxic properties of cadmium nanoparticles (Cd NPs) produced using Artemisia persica extract combined with microwave irradiation (850 W). The obtained results showed that the Cd NPs were hexagonal in shape and their size was in the range of 11.2–18.6 nm. The attained results of antioxidant activity showed that at concentrations ranging from 10 to 2560 µg mL −1 , there was no considerable difference between scavenging effect of Cd NPs and ascorbic acid ( p  > 0.05). For A549, 3T3, HT-29, MCF-7, and U87 cells exposed to Cd NPs, the IC 50 was measured to be 47.2 ± 1.2 µg mL −1 , 10.6 ± 1 µg mL −1 , 133.5 ± 1.3 µg mL −1 , 1.8 ± 0.7 µg mL −1 , and 62.9 ± 3.3 µg mL −1 , respectively. Generally, Cd NPs exhibited lower cytotoxicity and higher antioxidant effect in comparison to cadmium ions which further studies should perform to find about the related mechanisms.