Effect of Chlorella vulgaris supplementation with eccentric exercise on serum interleukin 6 and insulin resistance in overweight men

Purpose Overweight can lead to the down-regulation of insulin sensitivity and cytokine profile. In this regard, non-pharmacological interventions such as exercise and supplementation are recommended. Therefore, the aim of this study was to investigate the synergistic effect of Chlorella vulgaris sup...

Full description

Saved in:
Bibliographic Details
Published in:Sport sciences for health 2020-09, Vol.16 (3), p.543-549
Main Authors: Samadi, Mohammad, Shirvani, Hossein, Shafeie, Ali Akbar
Format: Article
Language:English
Subjects:
Antioxidants
Body mass index
Cytokines
Diabetes
Dietary supplements
Enzymes
Exercise
Fitness equipment
Fitness training programs
Human Physiology
Insulin resistance
Medicine
Medicine & Public Health
Metabolic Diseases
Obesity
Original Article
Overweight
Physical fitness
Polyphenols
Range of motion
Running
Sports Medicine
Tumor necrosis factor-TNF
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose Overweight can lead to the down-regulation of insulin sensitivity and cytokine profile. In this regard, non-pharmacological interventions such as exercise and supplementation are recommended. Therefore, the aim of this study was to investigate the synergistic effect of Chlorella vulgaris supplementation with acute eccentric exercise on serum levels of interleukin-6 and insulin resistance in overweight men. Methods Thirty subjects (aged 22.8 ± 2.1 years, BMI 27.1 ± 9.6 kg/m 2 ) were randomly divided into three equal groups: exercise [just perform acute eccentric exercise test (AEE)], Chlorella vulgaris (for 7 days and then AEE), placebo (for 7 days and then AEE). Blood sampling was performed in 4 stages: day 1 (before supplementation) and day 7 (after supplementation), after AEE and 24 h after AEE. Subjects of the supplement group received Chlorella vulgaris supplement (300 mg) four times daily for 1 week, and the placebo group consumed similar dextrose tablets. Exercise groups just perform AEE. AEE test included a 20-min treadmill run at a speed of 9 km/h with a negative 10% slope. Serum levels of IL-6, insulin, and glucose were measured by Elisa kit. Also, the hip circumference and knee range of motion (ROM) was measured at four stages. Results At the end of the study, there was a significant decrease in IL-6 levels in the Chlorella vulgari s group compared to the other two groups at 24 h after AEE test ( P  
ISSN:1824-7490
1825-1234
DOI:10.1007/s11332-020-00656-0