Recent advances in wireless epicortical and intracortical neuronal recording systems

• Published in: Science China. Information sciences 2022-04, Vol.65 (4), p.140401, Article 140401
• Main Authors: Ji, Bowen, Liang, Zekai, Yuan, Xichen, Xu, Honglai, Wang, Minghao, Yin, Erwei, Guo, Zhejun, Wang, Longchun, Zhou, Yuhao, Feng, Huicheng, Chang, Honglong, Liu, Jingquan
• Format: Article
• Language: English
• Subjects: Computer Science; Data transmission; Electrodes; Human-computer interface; Information Systems and Communication Service; Neurological diseases; Recording; Review; System effectiveness
• ISSN: 1674-733X; 1869-1919
• DOI: 10.1007/s11432-021-3373-1

An implantable brain-computer interface (BCI) has proven to be effective in the field of sensory and motor function restoration and in the treatment of neurological disorders. Using a BCI recording system, we can transform current methods of human interaction with machines and the environment, especially to help those with cognitive and mobility disabilities regain mobility and reintegrate into society. However, most reported work has focused on a simple aspect of the whole system, such as electrodes, circuits, or data transmission, and only a very small percentage of systems are wireless. A miniature, lightweight, wireless, implantable microsystem is key to realizing long-term, real-time, and stable monitoring on freely moving animals or humans in their natural conditions. Here, we summarize typical wireless recording systems, from recording electrodes, processing chips and controllers, wireless data transmission, and power supply to the system-level package for either epicortical electrocorticogram (ECoG) or intracortical local field potentials (LFPs)/spike acquisition, developed in recent years. Finally, we conclude with our vision of challenges in next-generation wireless neuronal recording systems for chronic and safe applications.