Sniffing lung cancer related biomarkers using an oxidized graphene SAW sensor

• Published in: Frontiers of physics 2016-04, Vol.11 (2), p.109-113, Article 116801
• Main Author: 张鑫方 张正伟 何焰兰 刘一星 黎双 方靖越 张学骜 彭刚
• Format: Article
• Language: English
• Subjects: Astronomy; Astrophysics and Cosmology; Atomic; Biomarkers; Circuit design; Condensed Matter Physics; decane; Diagnosis; Environmental assessment; Gas sensors; Graphene; graphene oxide; Insertion loss; Lung cancer; lung-cancer biomarker; Molecular; Network analysers; Optical and Plasma Physics; Organic compounds; Particle and Nuclear Physics; Physics; Physics and Astronomy; Research Article; SAW gas sensor; Signal detection; Surface acoustic waves; VOCs; Volatile organic compounds; 信号检测电路; 挥发性有机化合物; 检测装置; 气体传感器; 氧化石墨; 生物标志物; 矢量网络分析仪; 肺癌
• ISSN: 2095-0462; 2095-0470
• DOI: 10.1007/s11467-015-0519-4

Decane is one of the volatile organic compounds (VOCs) in human breath. Successful detection of decane in human breath has vast prospects for early lung cancer diagnosis. In this paper, a novel detecting device based on a filter surface acoustic wave (SAW) gas sensor is presented. SAW sensors coated with a thin oxidized graphene film were used to detect decane in parts per million (ppm) concentrations. Control and signal detection circuits were designed using a vector network analyzer with a detection resolution of insertion loss down to 0.0001 dB. The results showed that the SAW sensor could respond quickly with great sensitivity when exposed to 0.2 ppm decane. This device shows tremendous potential in medical diagnosis and environmental assessment.