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Effect of electroacupuncture at the Pericardium Meridian on the heart function of volunteers with acute hypoxia

Objective To study the effect of electroacupuncture (EA) at the Pericardium Meridian on the heart function of volunteers with acute hypoxia, and to provide scientific evidence for the acupoints selection along the affected meridian in acupuncture-moxibustion therapy. Methods Based on a self-control...

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Published in:Journal of acupuncture and tuina science 2017-10, Vol.15 (5), p.354-359
Main Authors: Dong, Ya-qin, Huang, Qian-ru, Chen, Qi, Chen, Ming, Xu, Jin-sen
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Huang, Qian-ru
Chen, Qi
Chen, Ming
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description Objective To study the effect of electroacupuncture (EA) at the Pericardium Meridian on the heart function of volunteers with acute hypoxia, and to provide scientific evidence for the acupoints selection along the affected meridian in acupuncture-moxibustion therapy. Methods Based on a self-control design, eighteen healthy volunteers were recruited in the study. Points from the Pericardium Meridian [Neiguan (PC 6), Ximen (PC 4), Quze (PC 3) and Tianquan (PC 2)], non-Pericardium Meridian point [Shousanli (LI 10)], non-meridian and non-acupoint points [1.0-1.5 cm lateral to Neiguan (PC 6) and Ximen (PC 4), respectively on both sides], and a blank control (only inhaling low-oxygen gas without EA stimulation) were selected to observe, once every week, 10 sessions in total, and only 1 acupoint was observed once. The volunteers inhaled low-oxygen gas mixture (10.8% O 2 and 89.2% N 2 ) for 30 min to imitate acute hypoxia. EA was conducted when the gas mixture was inhaled for 10 min and then lasted for 20 min; meanwhile, hemodynamic indexes such as cardiac output (CO), cardiac index (CI), systemic vascular resistance (SVR), systemic vascular resistance index (SVRI), left cardiac work (LCW), left cardiac work index (LCWI) and heart rate (HR) were recorded on a hemodynamic monitor. Results EA at the acupoints of Pericardium Meridian significantly down-regulated the increased CO/CI, LCW/LCWI, and HR ( P
doi_str_mv 10.1007/s11726-017-1027-6
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Methods Based on a self-control design, eighteen healthy volunteers were recruited in the study. Points from the Pericardium Meridian [Neiguan (PC 6), Ximen (PC 4), Quze (PC 3) and Tianquan (PC 2)], non-Pericardium Meridian point [Shousanli (LI 10)], non-meridian and non-acupoint points [1.0-1.5 cm lateral to Neiguan (PC 6) and Ximen (PC 4), respectively on both sides], and a blank control (only inhaling low-oxygen gas without EA stimulation) were selected to observe, once every week, 10 sessions in total, and only 1 acupoint was observed once. The volunteers inhaled low-oxygen gas mixture (10.8% O 2 and 89.2% N 2 ) for 30 min to imitate acute hypoxia. EA was conducted when the gas mixture was inhaled for 10 min and then lasted for 20 min; meanwhile, hemodynamic indexes such as cardiac output (CO), cardiac index (CI), systemic vascular resistance (SVR), systemic vascular resistance index (SVRI), left cardiac work (LCW), left cardiac work index (LCWI) and heart rate (HR) were recorded on a hemodynamic monitor. Results EA at the acupoints of Pericardium Meridian significantly down-regulated the increased CO/CI, LCW/LCWI, and HR ( P &lt;0.05), and significantly up-regulated the decreased SVR/SVRI in hypoxia ( P &lt;0.05); EA at other meridian acupoints or at non-meridian and non-acupoint points didn’t produce such effects. Conclusion EA at the Pericardium Meridian can obviously improve the cardiac hyper-activation caused by acute hypoxia in healthy volunteers.</description><identifier>ISSN: 1672-3597</identifier><identifier>EISSN: 1993-0399</identifier><identifier>DOI: 10.1007/s11726-017-1027-6</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Acupuncture ; Clinical Study ; Electroacupuncture ; Hemodynamics ; Hypoxia ; Medicine ; Medicine &amp; Public Health ; Pericardium</subject><ispartof>Journal of acupuncture and tuina science, 2017-10, Vol.15 (5), p.354-359</ispartof><rights>Shanghai Research Institute of Acupuncture and Meridian and Springer-Verlag GmbH Germany 2017</rights><rights>Shanghai Research Institute of Acupuncture and Meridian and Springer-Verlag GmbH Germany 2017.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c316t-485e8f16859cb09ca94e1ea5fef904f5bb8f10a4efe9da23fac256c537b8d4313</citedby><cites>FETCH-LOGICAL-c316t-485e8f16859cb09ca94e1ea5fef904f5bb8f10a4efe9da23fac256c537b8d4313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Dong, Ya-qin</creatorcontrib><creatorcontrib>Huang, Qian-ru</creatorcontrib><creatorcontrib>Chen, Qi</creatorcontrib><creatorcontrib>Chen, Ming</creatorcontrib><creatorcontrib>Xu, Jin-sen</creatorcontrib><title>Effect of electroacupuncture at the Pericardium Meridian on the heart function of volunteers with acute hypoxia</title><title>Journal of acupuncture and tuina science</title><addtitle>J. Acupunct. Tuina. Sci</addtitle><description>Objective To study the effect of electroacupuncture (EA) at the Pericardium Meridian on the heart function of volunteers with acute hypoxia, and to provide scientific evidence for the acupoints selection along the affected meridian in acupuncture-moxibustion therapy. Methods Based on a self-control design, eighteen healthy volunteers were recruited in the study. Points from the Pericardium Meridian [Neiguan (PC 6), Ximen (PC 4), Quze (PC 3) and Tianquan (PC 2)], non-Pericardium Meridian point [Shousanli (LI 10)], non-meridian and non-acupoint points [1.0-1.5 cm lateral to Neiguan (PC 6) and Ximen (PC 4), respectively on both sides], and a blank control (only inhaling low-oxygen gas without EA stimulation) were selected to observe, once every week, 10 sessions in total, and only 1 acupoint was observed once. The volunteers inhaled low-oxygen gas mixture (10.8% O 2 and 89.2% N 2 ) for 30 min to imitate acute hypoxia. EA was conducted when the gas mixture was inhaled for 10 min and then lasted for 20 min; meanwhile, hemodynamic indexes such as cardiac output (CO), cardiac index (CI), systemic vascular resistance (SVR), systemic vascular resistance index (SVRI), left cardiac work (LCW), left cardiac work index (LCWI) and heart rate (HR) were recorded on a hemodynamic monitor. Results EA at the acupoints of Pericardium Meridian significantly down-regulated the increased CO/CI, LCW/LCWI, and HR ( P &lt;0.05), and significantly up-regulated the decreased SVR/SVRI in hypoxia ( P &lt;0.05); EA at other meridian acupoints or at non-meridian and non-acupoint points didn’t produce such effects. 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Acupunct. Tuina. Sci</stitle><date>2017-10-01</date><risdate>2017</risdate><volume>15</volume><issue>5</issue><spage>354</spage><epage>359</epage><pages>354-359</pages><issn>1672-3597</issn><eissn>1993-0399</eissn><abstract>Objective To study the effect of electroacupuncture (EA) at the Pericardium Meridian on the heart function of volunteers with acute hypoxia, and to provide scientific evidence for the acupoints selection along the affected meridian in acupuncture-moxibustion therapy. Methods Based on a self-control design, eighteen healthy volunteers were recruited in the study. Points from the Pericardium Meridian [Neiguan (PC 6), Ximen (PC 4), Quze (PC 3) and Tianquan (PC 2)], non-Pericardium Meridian point [Shousanli (LI 10)], non-meridian and non-acupoint points [1.0-1.5 cm lateral to Neiguan (PC 6) and Ximen (PC 4), respectively on both sides], and a blank control (only inhaling low-oxygen gas without EA stimulation) were selected to observe, once every week, 10 sessions in total, and only 1 acupoint was observed once. The volunteers inhaled low-oxygen gas mixture (10.8% O 2 and 89.2% N 2 ) for 30 min to imitate acute hypoxia. EA was conducted when the gas mixture was inhaled for 10 min and then lasted for 20 min; meanwhile, hemodynamic indexes such as cardiac output (CO), cardiac index (CI), systemic vascular resistance (SVR), systemic vascular resistance index (SVRI), left cardiac work (LCW), left cardiac work index (LCWI) and heart rate (HR) were recorded on a hemodynamic monitor. Results EA at the acupoints of Pericardium Meridian significantly down-regulated the increased CO/CI, LCW/LCWI, and HR ( P &lt;0.05), and significantly up-regulated the decreased SVR/SVRI in hypoxia ( P &lt;0.05); EA at other meridian acupoints or at non-meridian and non-acupoint points didn’t produce such effects. Conclusion EA at the Pericardium Meridian can obviously improve the cardiac hyper-activation caused by acute hypoxia in healthy volunteers.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><doi>10.1007/s11726-017-1027-6</doi><tpages>6</tpages></addata></record>
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subjects Acupuncture
Clinical Study
Electroacupuncture
Hemodynamics
Hypoxia
Medicine
Medicine & Public Health
Pericardium
title Effect of electroacupuncture at the Pericardium Meridian on the heart function of volunteers with acute hypoxia
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