Cleft lip pathology diagnosis and foetal landmark extraction via 3D geometrical analysis

This work proposes a methodology to automatically diagnose and formalize prenatal cleft lip with representative key points and identify the type of defect (unilateral, bilateral, right, or left) in three-dimensional ultrasonography (3D US). Differential Geometry has been used as a framework for desc...

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Bibliographic Details
Published in:International journal on interactive design and manufacturing 2017-02, Vol.11 (1), p.1-18
Main Authors: Moos, Sandro, Marcolin, Federica, Tornincasa, Stefano, Vezzetti, Enrico, Violante, Maria Grazia, Fracastoro, Giulia, Speranza, Domenico, Padula, Francesco
Format: Article
Language:English
Subjects:
Algorithms
CAE) and Design
Computer-Aided Engineering (CAD
Defects
Diagnosis
Differential geometry
Electronics and Microelectronics
Engineering
Engineering Design
Fetuses
Industrial Design
Instrumentation
Mechanical Engineering
Original Paper
Postpartum period
Ultrasonic imaging
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Summary:This work proposes a methodology to automatically diagnose and formalize prenatal cleft lip with representative key points and identify the type of defect (unilateral, bilateral, right, or left) in three-dimensional ultrasonography (3D US). Differential Geometry has been used as a framework for describing facial shapes and curvatures. Then, descriptors coming from this field are employed for identifying the typical key points of the defect and its dimensions. The descriptive accurateness of these descriptors has allowed us to automatically extract reference points, quantitative distances, labial profiles, and to provide information about facial asymmetry. Seventeen foetal faces, nine of healthy foetuses and eight with different types of cleft lips, have been obtained through a Voluson system and used for testing the algorithm. In case no defect is present, the algorithm detects thirteen standard facial soft-tissue landmarks. This would help ultrasonographists and future mothers in identifying the most salient points of the forthcoming baby. This algorithm has been designed to support practitioners in identifying and classifying cleft lips. The gained results have shown that differential geometry may be a valuable tool for describing faces and for diagnosis.
ISSN:1955-2513
1955-2505
DOI:10.1007/s12008-014-0244-1